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简明综述:人工智能与生物医学纳米材料的协同作用使纳米医学更强大。

A concise review: the synergy between artificial intelligence and biomedical nanomaterials that empowers nanomedicine.

机构信息

Precision Health Program,, Michigan State University, East Lansing, MI, United States of America.

Lyman Briggs College, Michigan State University, East Lansing, MI, United States of America.

出版信息

Biomed Mater. 2021 Aug 5;16(5). doi: 10.1088/1748-605X/ac15b2.

Abstract

Nanomedicine has recently experienced unprecedented growth and development. However, the complexity of operations at the nanoscale introduces a layer of difficulty in the clinical translation of nanodrugs and biomedical nanotechnology. This problem is further exacerbated when engineering and optimizing nanomaterials for biomedical purposes. To navigate this issue, artificial intelligence (AI) algorithms have been applied for data analysis and inference, allowing for a more applicable understanding of the complex interaction amongst the abundant variables in a system involving the synthesis or use of nanomedicine. Here, we report on the current relationship and implications of nanomedicine and AI. Particularly, we explore AI as a tool for enabling nanomedicine in the context of nanodrug screening and development, brain-machine interfaces and nanotoxicology. We also report on the current state and future direction of nanomedicine and AI in cancer, diabetes, and neurological disorder therapy.

摘要

纳米医学最近经历了前所未有的增长和发展。然而,纳米尺度操作的复杂性给纳米药物和生物医学纳米技术的临床转化带来了一层困难。当为生物医学目的而设计和优化纳米材料时,这个问题更加严重。为了解决这个问题,人工智能(AI)算法已被应用于数据分析和推理,从而更适当地理解在涉及纳米医学的合成或使用的系统中,丰富变量之间的复杂相互作用。在这里,我们报告了纳米医学和人工智能的当前关系和影响。特别地,我们探索了人工智能作为一种工具,在纳米药物筛选和开发、脑机接口和纳米毒理学方面使纳米医学成为可能。我们还报告了癌症、糖尿病和神经障碍治疗中纳米医学和人工智能的当前状态和未来方向。

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