Delft University of Technology, Delft, the Netherlands.
Human Organ and Disease Model Technologies (hDMT), the Netherlands.
Stem Cell Reports. 2021 Sep 14;16(9):2037-2043. doi: 10.1016/j.stemcr.2021.06.015. Epub 2021 Jul 22.
Organ-on-chip (OoC) technology is thriving thanks to stem cells availability and international OoC programs. Concerted standardization, qualification, and independent testing of devices are needed to coherently develop OoC technology further and fulfill its potential in drug development, disease modeling, and personalized medicine. The OoC roadmap can lead the way forward.
器官芯片(OoC)技术得益于干细胞的可用性和国际 OoC 计划而蓬勃发展。需要对设备进行协调的标准化、资格认证和独立测试,以协调地进一步开发 OoC 技术,并发挥其在药物开发、疾病建模和个性化医疗方面的潜力。OoC 路线图可以指明前进的方向。