Mughal Mohsin S, Kaur Ikwinder Preet, Akbar Hafsa, Abbas Syed H, Angi Priya
Internal Medicine, Monmouth Medical Center, Long Branch, USA.
Department of Internal Medicine, Abington Jefferson Hospital, Abington, USA.
Cureus. 2021 Jun 23;13(6):e15872. doi: 10.7759/cureus.15872. eCollection 2021 Jun.
A 74-year-old male with a history of mild cognitive impairment presented to the emergency department with failure to thrive and generalized weakness. He was having difficulty swallowing leading to 30 pounds of unintentional weight loss in the last three months. His social history was significant for 12.5 pack-year smoking and drinking (two to three glasses of wine/day). The oral cavity examination revealed a large (3 × 2 cm) defect with the erythematous border that encompassed the mid-palatal structures and emanated from the hard palate into his nasal cavity. Auto-immune work-up was negative. Palatal biopsy showed squamous cell carcinoma (SCC; well-differentiated). A diagnosis of locally advanced (stage IVa) oral cavity squamous cell carcinoma (OSCC) was made based on PET scan findings. A palatal obturator (prosthesis) was placed to improve his eating, prevent regurgitation. The patient opted for palliative care and did not want to pursue further treatment. He was discharged home with a regular follow-up visit.
一名74岁男性,有轻度认知障碍病史,因身体衰弱和全身无力就诊于急诊科。他吞咽困难,在过去三个月内非故意体重减轻了30磅。他的社会史显示有12.5包年的吸烟和饮酒史(每天喝两到三杯葡萄酒)。口腔检查发现一个大的(3×2厘米)缺损,边界呈红斑状,累及腭中部结构,从硬腭延伸至鼻腔。自身免疫检查结果为阴性。腭部活检显示为鳞状细胞癌(SCC;高分化)。根据PET扫描结果,诊断为局部晚期(IVa期)口腔鳞状细胞癌(OSCC)。放置了腭部阻塞器(假体)以改善他的进食情况,防止反流。患者选择了姑息治疗,不想进一步接受治疗。他出院回家并定期随访。