Health Sciences University, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
Acibadem University School of Medicine Atakent Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
Eur J Obstet Gynecol Reprod Biol. 2021 Sep;264:254-258. doi: 10.1016/j.ejogrb.2021.07.037. Epub 2021 Jul 24.
Endometriosis is a disease that significantly affects the quality of life of patients. Continuous pelvic pain seen in patients disrupts their well-being. The aim of this study is to examine the changes in depression and sleep disorders in patients with endometriosis before and after the operation.
Forty-two women aged 18-49 with an indication for operation due to the diagnosis of stage 4 endometriosis and without a known psychiatric disorder were included in the study. Pittsburgh Sleep Quality Index and Beck Depression Inventory were used to compare sleep quality and mood of endometriosis patients before and after surgery.
The mean age of the patients was 33.8 ± 7.6. The mean BMI of the patients was 24.6 ± 4.1. Endometrioma diameter was 248.42 ± 95.7 cm3 in patients with poor sleep quality, while it was 296.11 ± 271.53 cm3 in patients with good sleep quality, and a significant difference was observed (p < 0.05). Poor sleep quality and severe depression were significantly higher in patients with infertility complaints. It was observed that sleep quality was not significantly correlated with bilateral endometrioma, a nodule in the Douglas, sacrouterine tenderness and mean ASRM scores (p > 0.05). A significant decrease in depression complaints and a significant increase in sleep quality were observed in patients who underwent stage-4 endometriosis surgery (p < 0.05).
We showed that there was a significant increase in sleep quality and a significant decrease in depression symptoms in patients who underwent stage-4 endometriosis surgery. Since endometriosis affects the social life of patients in many ways, it is necessary to increase the knowledge and experience about the treatment of endometriosis with larger studies to be done. We believe that surgical treatment can reduce social problems and increase the quality of life of endometriosis patients.
子宫内膜异位症是一种严重影响患者生活质量的疾病。患者持续的盆腔疼痛会干扰其健康状况。本研究旨在探讨子宫内膜异位症患者手术前后抑郁和睡眠障碍的变化。
本研究纳入了 42 名年龄在 18-49 岁之间、因诊断为 4 期子宫内膜异位症而需要手术且无已知精神疾病的女性患者。使用匹兹堡睡眠质量指数和贝克抑郁量表比较手术前后子宫内膜异位症患者的睡眠质量和情绪。
患者的平均年龄为 33.8±7.6 岁，平均 BMI 为 24.6±4.1。睡眠质量差的患者的子宫内膜异位瘤直径为 248.42±95.7cm3，而睡眠质量好的患者的直径为 296.11±271.53cm3，差异有统计学意义（p<0.05）。有不孕主诉的患者中，睡眠质量差和重度抑郁的比例显著更高。结果还表明，睡眠质量与双侧子宫内膜异位瘤、Douglas 结节、骶耻韧带压痛和 ASRM 评分平均值均无显著相关性（p>0.05）。接受 4 期子宫内膜异位症手术的患者中，抑郁主诉显著减少，睡眠质量显著提高（p<0.05）。
我们发现，接受 4 期子宫内膜异位症手术的患者睡眠质量显著提高，抑郁症状显著减轻。由于子宫内膜异位症在许多方面影响患者的社交生活，需要通过更大规模的研究来增加对子宫内膜异位症治疗的认识和经验。我们相信手术治疗可以减少社会问题，提高子宫内膜异位症患者的生活质量。
