Department of Psychology, Catholic University of the Sacred Heart, Largo Agostino Gemelli 1, Milan 20123, Italy.
Gynecology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 12, Milan 20122, Italy.
Reprod Biomed Online. 2021 Dec;43(6):1027-1034. doi: 10.1016/j.rbmo.2021.08.011. Epub 2021 Aug 20.
What are the associations between endometriosis, pelvic pain symptoms, fatigue and sleep? Psychological health and quality of life in endometriosis patients with good versus bad quality of sleep were also examined.
This matched pair case-control study included 123 consecutive endometriosis patients and 123 women without a history of endometriosis (matched to patients for age and body mass index). Endometriosis-related pelvic pain severity was rated on a 0-10 numerical rating scale. Fatigue was measured on a 1-5 Likert scale. Women also completed a set of self-report questionnaires for assessing sleep disturbances (Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Insomnia Severity Index), psychological health (Hospital Anxiety and Depression Scale) and quality of life (Short Form-12).
Painful endometriosis had an impact on fatigue (P = 0.006; η = 0.041) and sleep (P < 0.001; η = 0.051). Women with painful endometriosis reported significantly greater fatigue, poorer quality of sleep, higher daytime sleepiness and more severe insomnia than women without significant pain symptoms and controls. Poorer quality of sleep among endometriosis patients was associated with greater fatigue (P < 0.001; η = 0.130), poorer psychological health (P < 0.001; η = 0.135), and lower quality of life (P < 0.001; η = 0.240).
Pelvic pain (rather than endometriosis in itself) is associated with fatigue and sleep disturbances, with poor sleep having a detrimental impact on women's psychological health and quality of life.
子宫内膜异位症、盆腔疼痛症状、疲劳和睡眠之间有什么关联？还检查了子宫内膜异位症患者中睡眠质量好与差的心理健康和生活质量。
这项配对病例对照研究纳入了 123 例连续的子宫内膜异位症患者和 123 例无子宫内膜异位症病史的女性（按年龄和体重指数与患者匹配）。子宫内膜异位症相关盆腔疼痛严重程度用 0-10 数字评分量表评定。疲劳用 1-5 级 Likert 量表评定。女性还完成了一套评估睡眠障碍的自我报告问卷（匹兹堡睡眠质量指数、爱泼沃斯嗜睡量表、失眠严重程度指数）、心理健康（医院焦虑和抑郁量表）和生活质量（简明健康状况调查问卷 12 项）。
疼痛性子宫内膜异位症对疲劳（P=0.006；η=0.041）和睡眠（P<0.001；η=0.051）有影响。有疼痛症状的子宫内膜异位症女性比无症状疼痛的女性和对照组报告疲劳感更明显、睡眠质量更差、白天嗜睡更严重、失眠更严重。子宫内膜异位症患者睡眠质量较差与疲劳（P<0.001；η=0.130）、心理健康较差（P<0.001；η=0.135）和生活质量较低（P<0.001；η=0.240）有关。
盆腔疼痛（而非子宫内膜异位症本身）与疲劳和睡眠障碍相关，睡眠质量差对女性的心理健康和生活质量有不利影响。
