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对印度马哈拉施特拉邦一家三级护理医院收治的新冠肺炎患者的死亡率和生存率分析。

An analysis of mortality and survival of COVID 19 patients admitted to a tertiary care hospital in Maharashtra, India.

作者信息

Bobdey Saurabh, Chawla Naveen, Behera Vineet, Ray Sougat, Ilankumaran M, Koshy George, Kaushik S K

机构信息

Professor, Department of Community Medicine, Armed Forces Medical College, Pune, India.

DGMS (Navy), O/o DGMS (N), IHQ MoD (Navy), 'A' Wing, Sena Bhawan, New Delhi, India.

出版信息

Med J Armed Forces India. 2021 Jul;77(Suppl 2):S353-S358. doi: 10.1016/j.mjafi.2021.02.004. Epub 2021 Jul 26.

Abstract

BACKGROUND

After nine months of responding to the coronavirus disease-19 (COVID-19) pandemic, the scientific fraternity is yet to unravel the mystery of those who are at most risk from mortality. Despite resistance to wear masks, the global public health response has beaten the grimmer projections of millions of deaths. The present study seeks to analyze the survival of COVID-19 patients at a tertiary care hospital and identify the risk factors of mortality.

METHODS

Medical records of 1233 RT PCR confirmed COVID-19 patients admitted in a tertiary care hospital between 01 April and 30 September 2020 were retrospectively analyzed for calculating overall survival and to investigate the independent predictors of survival of COVID-19 patients.

RESULTS

There were 72 (5.8%) deaths; which occurred in 24.9% of the elderly (age > 60yrs) people (P < 0.001), 76.0% in people with multiple comorbidities (having more than one comorbidity) (P < 0.001), 75.6% in people with diabetes (P < 0.001), and 75.5% in people with hypertension (P < 0.001). A significantly higher risk of mortality was observed in elderly patients, patients with comorbidities, and patients requiring oxygen while admitted in the hospital.

CONCLUSION

Survival reflects the cure rates and is used by health professionals and policymakers to plan and implement disease control measures. The insights provided by the study would help facilitate the identification of patients at risk and timely provision of specialized care for the prevention of adverse outcomes in the hospital setting.

摘要

背景

在应对新型冠状病毒肺炎(COVID-19)疫情九个月后,科学界仍未解开哪些人死亡风险最高的谜团。尽管有人抵触戴口罩,但全球公共卫生应对措施已超过对数百万死亡人数的更严峻预测。本研究旨在分析一家三级医院中COVID-19患者的生存情况,并确定死亡风险因素。

方法

回顾性分析2020年4月1日至9月30日期间在一家三级医院住院的1233例经逆转录聚合酶链反应(RT PCR)确诊的COVID-19患者的病历,以计算总体生存率,并调查COVID-19患者生存的独立预测因素。

结果

有72例(5.8%)死亡;其中24.9%的老年人(年龄>60岁)死亡(P<0.001),76.0%的患有多种合并症(有一种以上合并症)的人死亡(P<0.001),75.6%的糖尿病患者死亡(P<0.001),75.5%的高血压患者死亡(P<0.001)。在老年患者、合并症患者以及住院时需要吸氧的患者中,观察到显著更高的死亡风险。

结论

生存率反映了治愈率,卫生专业人员和政策制定者用它来规划和实施疾病控制措施。该研究提供的见解将有助于识别高危患者,并及时提供专门护理,以预防医院环境中的不良后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375c/8346834/8315aec5965d/gr1.jpg

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