新冠疫情期间儿童的身体质量指数变化：一项基于电子健康记录的回顾性队列研究。
Pediatric BMI changes during COVID-19 pandemic: An electronic health record-based retrospective cohort study.
作者信息
Brooks Corinne G, Spencer Jessica R, Sprafka J Michael, Roehl Kimberly A, Ma Junjie, Londhe Ajit A, He Fang, Cheng Alvan, Brown Carolyn A, Page John
机构信息
Center for Observational Research, Amgen, Inc., 1000 E Oaks Blvd, One Amgen Ctr. Dr. M/S 24-1-C, Thousand Oaks, California 91362, United States.
SimulStat Inc, Solana Beach, 1000 E Oaks Blvd, One Amgen Ctr. Dr. M/S 24-1-C, Thousand Oaks, California 91362, United States.
出版信息
EClinicalMedicine. 2021 Jul 16;38:101026. doi: 10.1016/j.eclinm.2021.101026. eCollection 2021 Aug.
BACKGROUND
Beginning March 2020, the COVID-19 pandemic has disrupted different aspects of life. The impact on children's rate of weight gain has not been analysed.
METHODS
In this retrospective cohort study, we used United States (US) Electronic Health Record (EHR) data from Optum® to calculate the age- and sex- adjusted change in BMI (∆BMI) in individual 6-to-17-year-old children between two well child checks (WCCs). The mean of individual ∆BMI during 2017-2020 was calculated by month. For September-December WCCs, the mean of individual ∆BMI (overall and by subgroup) was reported for 2020 and 2017-2019, and the impact of 2020 vs 2017-2019 was tested by multivariable linear regression.
FINDINGS
The mean [95% Confidence Interval - CI] ∆BMI in September-December of 2020 was 0·62 [0·59,0·64] kg/m, compared to 0·31 [0·29, 0·32] kg/m in previous years. The increase was most prominent in children with pre-existing obesity (1·16 [1·07,1·24] kg/m in 2020 versus 0·56 [0·52,0·61] kg/m in previous years), Hispanic children (0·93 [0·84,1·02] kg/m in 2020 versus 0·41 [0·36,0·46] kg/m in previous years), and children who lack commercial insurance (0·88 [0·81,0·95] kg/m in 2020 compared to 0·43 [0·39,0·47] kg/m in previous years). ∆BMI accelerated most in ages 8-12 and least in ages 15-17.
INTERPRETATION
Children's rate of unhealthy weight gain increased notably during the COVID-19 pandemic across demographic groups, and most prominently in children already vulnerable to unhealthy weight gain. This data can inform policy decisions critical to child development and health as the pandemic continues to unfold.
FUNDING
Amgen, Inc.
背景
自2020年3月起，新冠疫情扰乱了生活的方方面面。但疫情对儿童体重增加率的影响尚未得到分析。
方法
在这项回顾性队列研究中，我们使用了来自Optum®的美国电子健康记录（EHR）数据，以计算6至17岁儿童在两次健康体检（WCC）期间经年龄和性别调整后的体重指数变化（∆BMI）。按月份计算了2017 - 2020年期间个体∆BMI的平均值。对于9月至12月的健康体检，报告了2020年以及2017 - 2019年个体∆BMI（总体及各亚组）的平均值，并通过多变量线性回归检验了2020年与2017 - 2019年的差异。
结果
2020年9月至12月的平均[95%置信区间 - CI]∆BMI为0.62[0.59, 0.64]kg/m²，而前几年为0.31[0.29, 0.32]kg/m²。体重增加在已有肥胖问题的儿童中最为显著（2020年为1.16[1.07, 1.24]kg/m²，前几年为0.56[0.52, 0.61]kg/m²）、西班牙裔儿童（2020年为0.93[0.84, 1.02]kg/m²，前几年为0.41[0.36, 0.46]kg/m²）以及缺乏商业保险的儿童（2020年为0.88[0.81, 0.95]kg/m²，前几年为0.43[0.39, 0.47]kg/m²）中最为明显。∆BMI在8至12岁儿童中加速最为明显，在15至17岁儿童中加速最少。
解读
在新冠疫情期间，各人口群体中儿童不健康体重增加率显著上升，在本就容易出现不健康体重增加的儿童中最为突出。随着疫情持续发展，这些数据可为关乎儿童发育和健康的政策决策提供参考。
资金来源
安进公司
Zotero 插件