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尿道成形术后颊黏膜移植物发生鳞状细胞癌：2例恶性退变报告

Squamous Cell Carcinoma Developing in a Buccal Mucosa Graft after Urethroplasty: A Report of 2 Cases of Malignant Degeneration.

作者信息

Massimo Catti, Simona Nappo Gerocarni, Barbara Tadini, Elisa Cerchia, Luisa Ferrero, Alessandro Gambella, Donatella Pacchioni, Teruzzi Elisabetta, Falcone Marco, Omidreza Sedigh, Paolo Gontero

机构信息

Paediatric Urology, Città Della Salute e Della Scienza Torino, Italy.

Pathology Unit, Department of Medical Sciences, Città Della Salute e Della Scienza Torino, Italy.

出版信息

Case Rep Urol. 2021 Jul 24;2021:5569373. doi: 10.1155/2021/5569373. eCollection 2021.

DOI:10.1155/2021/5569373
PMID:34350044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8328690/
Abstract

Buccal mucosa graft (BMG) was originally described in 1992 for the treatment of challenging cases of hypospadias (proximal or redo cases) and has gained increasingly popularity also when dealing with complicated urethral stenosis, as it is associated with a good outcome. The development of a malignancy in a BMG urethroplasty was reported for the first time in 2017. We report two more cases of a malignant degeneration of a BMG used in a urethroplasty to treat recurrent urethral stricture.

摘要

颊黏膜移植术（BMG）最初于1992年被描述用于治疗尿道下裂的复杂病例（近端或再次手术病例），并且在处理复杂尿道狭窄时也越来越受到欢迎，因为其疗效良好。2017年首次报道了BMG尿道成形术中发生恶性肿瘤的情况。我们报告另外两例在尿道成形术中使用BMG治疗复发性尿道狭窄时发生恶性退变的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25fc/8328690/542ac3747d71/CRIU2021-5569373.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25fc/8328690/080b781ff731/CRIU2021-5569373.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25fc/8328690/abf2a2819df7/CRIU2021-5569373.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25fc/8328690/542ac3747d71/CRIU2021-5569373.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25fc/8328690/080b781ff731/CRIU2021-5569373.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25fc/8328690/abf2a2819df7/CRIU2021-5569373.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25fc/8328690/542ac3747d71/CRIU2021-5569373.003.jpg

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本文引用的文献

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Current Disease Management of Primary Urethral Carcinoma.原发性尿道癌的现行疾病管理。
Eur Urol Focus. 2019 Sep;5(5):722-734. doi: 10.1016/j.euf.2019.07.001. Epub 2019 Jul 13.
2
Development of Squamous Cell Carcinoma of Buccal Mucosa Graft Used for Urethroplasty: A Case Report.用于尿道成形术的颊黏膜移植物发生鳞状细胞癌：一例报告
Urol Case Rep. 2016 Dec 11;10:60-62. doi: 10.1016/j.eucr.2016.11.002. eCollection 2017 Jan.
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Cancer of the oral cavity.口腔癌
Surg Oncol Clin N Am. 2015 Jul;24(3):491-508. doi: 10.1016/j.soc.2015.03.006. Epub 2015 Apr 15.
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EAU guidelines on primary urethral carcinoma.EAU 指南：原发性尿道癌
Eur Urol. 2013 Nov;64(5):823-30. doi: 10.1016/j.eururo.2013.03.044. Epub 2013 Apr 2.
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Autologous buccal mucosa graft for hypospadias repair: an initial report.自体颊黏膜移植修复尿道下裂：初步报告。
J Urol. 1992 Apr;147(4):1081-3; discussion 1083-4. doi: 10.1016/s0022-5347(17)37478-5.