Department of Orthopedics, Second Hospital of Jilin University, Changchun, 130041, China.
Dermatological Department, Second Hospital of Jilin University, Changchun, 130041, China.
Med Biol Eng Comput. 2021 Sep;59(9):1673-1689. doi: 10.1007/s11517-021-02361-7. Epub 2021 Aug 7.
Metal implants are widely used in the treatment of orthopedic diseases. However, owing to the mismatched elastic modulus of the bone and implants, stress shielding often occurs clinically which can result in failure of the implant or fractures around the implant. Topology optimization (TO) is a technique that can provide more efficient material distribution according to the objective function under the special load and boundary conditions. Several researchers have paid close attention to TO for optimal design of orthopedic implants. Thanks to the development of additive manufacturing (AM), the complex structure of the TO design can be fabricated. This article mainly focuses on the current stage of TO technique with respect to the global layout and hierarchical structure in orthopedic implants. In each aspect, diverse implants in different orthopedic fields related to TO design are discussed. The characteristics of implants, methods of TO, validation methods of the newly designed implants, and limitations of current research have been summarized. The review concludes with future challenges and directions for research. Wang TO design of global layout and local structure of implants in diverse fields of orthopedic.
金属植入物在骨科疾病的治疗中被广泛应用。然而，由于骨骼和植入物的弹性模量不匹配，临床上经常会发生应力遮挡，从而导致植入物失效或植入物周围骨折。拓扑优化（TO）是一种可以根据特殊负载和边界条件下的目标函数提供更有效材料分布的技术。许多研究人员已经关注到了 TO 技术在骨科植入物优化设计中的应用。得益于增材制造（AM）的发展，TO 设计的复杂结构可以被制造出来。本文主要关注的是 TO 技术在骨科植入物全局布局和层次结构方面的现状。在每个方面，都讨论了与 TO 设计相关的不同骨科领域中的不同植入物。总结了植入物的特点、TO 方法、新设计植入物的验证方法以及当前研究的局限性。最后，对未来的研究挑战和方向进行了总结。
Wang 对不同骨科领域的植入物的全局布局和局部结构进行了 TO 设计。
