Clapp Andrea N, DePold Hohler Anna
Tufts University School of Medicine, Boston, MA, USA.
Department of Neurology, St. Elizabeth's Medical Center, Brighton, MA, USA.
SAGE Open Med Case Rep. 2021 Jul 23;9:2050313X211034351. doi: 10.1177/2050313X211034351. eCollection 2021.
This case report describes a 46-year-old female with a history of multiple endocrine neoplasia type 1 syndrome status post-parathyroidectomy, thymectomy via robotic video-assisted thoracoscopic surgery, and pituitary adenoma resection presenting with parasympathetic hyperactivity and Parry-Romberg syndrome. Parry-Romberg syndrome is a rare disorder that manifests as facial hemiatrophy. Reported symptoms include cognitive dysfunction, olfactory hallucinations, and parasympathetic hyperactivity: miosis of the right eye, anhidrosis, diarrhea, urinary incontinence, bowel incontinence, and orthostatic hypotension. Previous reports have noted associations between Parry-Romberg syndrome and sympathetic hyperactivity and dysregulation. This case report focuses on an association between Parry-Romberg syndrome and unopposed parasympathetic activity.
本病例报告描述了一名46岁女性，有1型多发性内分泌腺瘤综合征病史，曾接受甲状旁腺切除术、经机器人电视辅助胸腔镜手术的胸腺切除术和垂体腺瘤切除术，现出现副交感神经功能亢进和帕里-罗姆伯格综合征。帕里-罗姆伯格综合征是一种罕见疾病，表现为面部半侧萎缩。报告的症状包括认知功能障碍、幻嗅和副交感神经功能亢进：右眼瞳孔缩小、无汗、腹泻、尿失禁、大便失禁和体位性低血压。既往报告指出帕里-罗姆伯格综合征与交感神经功能亢进和失调之间存在关联。本病例报告重点关注帕里-罗姆伯格综合征与无对抗性副交感神经活动之间的关联。
