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加纳抗逆转录病毒治疗服务的质量:对资源受限环境下艾滋病应对工作的影响。

Quality of antiretroviral therapy services in Ghana: Implications for the HIV response in resource-constrained settings.

作者信息

Alhassan Robert Kaba, Ketor Courage Edem, Ashinyo Anthony, Ashinyo Mary Eyram, Nutor Jerry John, Adjadeh Conrad, Sarkodie Emmanuel

机构信息

Centre for Health Policy and Implementation Research, Institute of Health Research, University of Health and Allied Sciences, Ho, Ghana.

Pharmacy Department, Jasikan District Hospital, Ghana Health Service, Jasikan, Ghana.

出版信息

SAGE Open Med. 2021 Jul 31;9:20503121211036142. doi: 10.1177/20503121211036142. eCollection 2021.

Abstract

OBJECTIVE

Number of People Living with Human Immune-deficiency Virus in Ghana is over 300,000 and unmet need for antiretroviral therapy is approximately 60%. This study sought to determine the quality of antiretroviral therapy services in selected ART sites in Ghana using the input-process-outcome approach.

METHODS

This is a descriptive cross-sectional case study that employed modified normative evaluation to assess quality of antiretroviral therapy services in the Oti and Volta regions of Ghana among People Living with HIV (n = 384) and healthcare providers (n = 16). The study was conducted from 11 March to 9 May 2019.

RESULTS

Resources for managing HIV clients were largely available with the exception of viral load machines, reagents for CD4 counts, and antifungals such as Fluconazole and Cotrimoxazole. Patients enrolled on antiretroviral therapy within 2 weeks was 71% and clients retained in care within 2 weeks of enrolment was 90%. Approximately 26% of enrolled clients recorded viral load suppression; 33% of People Living with HIV who were not insured with the National Health Insurance Scheme paid for some antiretrovirals and cotrimoxazole. Adherence to ART and Cotrimoxazole were 95% and 88%, respectively, using pill count on their last three visits. Time spent with clinical team was among the worst rated (mean = 2.98, standard deviation = 0.54) quality indicators by patients contrary to interpersonal relationship with health provider which was among the best rated (mean = 3.25, standard deviation = 0.41) indicators.

CONCLUSION

Observed quality care gaps could potentially reverse gains made in HIV prevention and control in Ghana if not addressed timely; an important value addition of this study is the novel application of input-process-outcome approach in the context of antiretroviral therapy services in Ghana. There is also the need for policy dialogue on inclusion of medications for prophylaxis in antiretroviral therapy on the National Health Insurance Scheme to promote adherence and retention.

摘要

目的

加纳感染人类免疫缺陷病毒的人数超过30万,抗逆转录病毒疗法的未满足需求约为60%。本研究旨在采用投入-过程-结果方法确定加纳选定抗逆转录病毒治疗点的抗逆转录病毒治疗服务质量。

方法

这是一项描述性横断面案例研究,采用改良的规范性评估来评估加纳奥蒂和沃尔特地区艾滋病毒感染者(n = 384)和医疗服务提供者(n = 16)的抗逆转录病毒治疗服务质量。该研究于2019年3月11日至5月9日进行。

结果

除病毒载量检测仪器、CD4计数试剂以及氟康唑和复方新诺明等抗真菌药物外,管理艾滋病毒患者的资源基本可用。两周内开始接受抗逆转录病毒治疗的患者比例为71%,登记后两周内仍接受治疗的患者比例为90%。约26%的登记患者实现了病毒载量抑制;33%未参加国家健康保险计划的艾滋病毒感染者自行支付了部分抗逆转录病毒药物和复方新诺明的费用。根据患者最后三次就诊时的药丸计数,抗逆转录病毒治疗和复方新诺明的依从性分别为95%和88%。患者对与临床团队相处时间的评价是最差的质量指标之一(平均值 = 2.98,标准差 = 0.54),而与医疗服务提供者的人际关系评价则是最佳指标之一(平均值 = 3.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9236/8326618/09978a553294/10.1177_20503121211036142-fig1.jpg

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