Pizzorno Joseph, Pizzorno Lara
Integr Med (Encinitas). 2021 Feb;20(1):10-17.
The environmental metals cadmium, lead, and mercury, and chemicals such as pesticides, phthalates, and bisphenols, disrupt bone metabolism in many ways. Body levels of these toxins directly correlate, in a dose-dependent manner, with risk of fracture and osteoporosis. This editorial provides a brief summary of key research showing mechanisms of damage, sources, and key strategies to decrease body load.
环境中的金属镉、铅和汞,以及农药、邻苯二甲酸盐和双酚等化学物质,会通过多种方式扰乱骨骼代谢。这些毒素在人体内的含量与骨折和骨质疏松症的风险呈剂量依赖性直接相关。这篇社论简要总结了关键研究,展示了损伤机制、来源以及降低体内毒素负荷的关键策略。