慢性血栓栓塞性肺动脉高压：床边诊断。
Chronic Thromboembolic Pulmonary Hypertension: the Bedside.
机构信息
Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Division of Pulmonary, Critical Care, and Sleep Medicine, Yale New Haven Hospital and Yale School of Medicine, New Haven, CT, USA.
出版信息
Curr Cardiol Rep. 2021 Aug 19;23(10):147. doi: 10.1007/s11886-021-01573-5.
PURPOSE OF REVIEW
Chronic thromboembolic pulmonary hypertension (CTEPH), included in group 4 PH, is an uncommon complication of acute pulmonary embolism (PE), in which emboli in the pulmonary vasculature do not resolve but rather form into an organized scar-like obstruction which can result in right ventricular (RV) failure. Here we provide an overview of current diagnosis and management of CTEPH.
RECENT FINDINGS
CTEPH management is complex with treatments that range from surgery, percutaneous interventions, to medical therapies. Current CTEPH medical therapies have largely been repurposed from pulmonary arterial hypertension (PAH). The diagnosis of CTEPH can be challenging, requiring a multimodality approach to differentiate from disease mimics. While these treatments improve symptoms, they may not reverse the underlying pathology of CTEPH.
目的综述
慢性血栓栓塞性肺动脉高压（CTEPH）属于 4 组肺动脉高压，是急性肺栓塞（PE）的一种罕见并发症，在这种情况下，肺血管中的栓子不会消散，而是形成有组织的瘢痕样阻塞，从而导致右心室（RV）衰竭。在这里，我们对 CTEPH 的当前诊断和治疗方法进行概述。
最新发现
CTEPH 的治疗方法复杂，包括手术、经皮介入和药物治疗。目前 CTEPH 的药物治疗主要是从肺动脉高压（PAH）中重新应用。CTEPH 的诊断具有挑战性，需要采用多模式方法来区分疾病模拟。虽然这些治疗方法可以改善症状，但它们可能无法逆转 CTEPH 的潜在病理。
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