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马疱疹病毒 1 型(马属医院)爆发的管理新见解。

New Insights into the Management of an EHV-1 (Equine Hospital) Outbreak.

机构信息

Hagyard Equine Medical Institute, 4250 Iron Works Pike, Lexington, KY 40511, USA.

Wolvega Equine Hospital, Stellingenweg 10, 8474EA Oldeholtpade, The Netherlands.

出版信息

Viruses. 2021 Jul 22;13(8):1429. doi: 10.3390/v13081429.

DOI:10.3390/v13081429
PMID:34452295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8402800/
Abstract

In May 2018, Wolvega Equine Hospital (WEH) experienced an EHV-1 outbreak. This outbreak caused significant economic losses and negative publicity for the hospital. How should hospitals prepare themselves for these outbreaks and prevent shedding of the virus on multiple neighboring premises? The hospital transformed most of its activities into mobile practice and the entire infected hospital population was moved to a separate remote location. The hospital was cleaned and disinfected according to the latest recommendations before reopening. Four neighboring professional equine businesses and three privately owned premises were affected by the spread of the virus from the hospital population and initiated quarantine restrictions. Equine hospitals should prepare themselves for EHV-1 outbreaks as the intake of the virus cannot be prevented. A management protocol should include public information protocols, swift client information and quarantine measures that ensure quick containment of the outbreak. Timely reopening of the hospital can be achieved by rehousing the contaminated population. It should also include good regulations with clients and a properly carried out release protocol. Equine sports organizations should establish sufficient vaccination coverage in order to decrease the frequency of EHV-1 outbreaks.

摘要

2018 年 5 月,Wolvega 马医院(WEH)爆发了马疱疹病毒 1 型(EHV-1)疫情。此次疫情给医院造成了重大经济损失和负面舆情。医院应如何为疫情做好准备,防止病毒在多个相邻场所传播?该医院将大部分活动转为移动实践,并将整个感染的医院人群转移到一个单独的偏远地点。在重新开放之前,医院按照最新建议进行了清洁和消毒。四家相邻的专业马术企业和三家私人场所受到医院人群传播病毒的影响,启动了隔离限制措施。马医院应做好应对 EHV-1 疫情的准备,因为无法预防病毒的摄入。管理方案应包括公众信息方案、迅速向客户提供信息和隔离措施,以确保迅速控制疫情。通过安置受污染的人群,可以及时重新开放医院。它还应包括与客户的良好规定和妥善执行的释放协议。马术运动组织应建立足够的疫苗接种覆盖率,以降低 EHV-1 疫情的频率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dca7/8402800/1d64efb32f59/viruses-13-01429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dca7/8402800/40e58c1d4db1/viruses-13-01429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dca7/8402800/1d64efb32f59/viruses-13-01429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dca7/8402800/40e58c1d4db1/viruses-13-01429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dca7/8402800/1d64efb32f59/viruses-13-01429-g002.jpg

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Am J Vet Res. 2017 Oct;78(10):1126-1139. doi: 10.2460/ajvr.78.10.1126.
3
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Microorganisms. 2025 Apr 12;13(4):891. doi: 10.3390/microorganisms13040891.
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6
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J Vet Intern Med. 2025 Jan-Feb;39(1):e17287. doi: 10.1111/jvim.17287.
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4
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8
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