State Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
State Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Curr Opin Pharmacol. 2021 Oct;60:200-207. doi: 10.1016/j.coph.2021.07.019. Epub 2021 Aug 10.
Lonicerae japonicae flos (LJF), known as Jin Yin Hua in Chinese, is one of the most commonly used traditional Chinese herbs and nutraceuticals. Nowadays, LJF is broadly applied in an array of afflictions, such as fever, sore throat, flu infection, cough, and arthritis, with the action mechanism to be elucidated. Here, we strove to summarize the main phytochemical components of LJF and review its updated pharmacological effects, including inhibition of inflammation, pyrexia, viruses, and bacteria, immunoregulation, and protection of the liver, nervous system, and heart, with a focus on the potential efficacy of LJF on coronavirus disease-2019 based on network pharmacology so as to fully underpin the utilization of LJF as a medicinal herb and a favorable nutraceutical in daily life.
金银花（Lonicerae japonicae flos，LJF），又名金花，是最常用的传统中药和营养保健品之一。如今，金银花广泛应用于发热、咽喉肿痛、流感感染、咳嗽和关节炎等多种疾病，其作用机制尚待阐明。在这里，我们试图总结金银花的主要植物化学成分，并综述其最新的药理作用，包括抑制炎症、发热、病毒和细菌、免疫调节以及对肝脏、神经系统和心脏的保护作用，重点关注基于网络药理学的金银花在 2019 冠状病毒病（COVID-19）方面的潜在疗效，以充分支持金银花作为药用植物和日常生活中有益的营养保健品的应用。
