• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人体尸体腰椎椎体块的轴向和旁轴向加载响应评估:对临床实践具有潜在临床意义的实验

Axial and para-axial loading response evaluation on human cadaver-harvested lumbar vertebral blocks: experiment with possible clinical implications for clinical practice.

作者信息

Iliescu Dan Marcel, Micu Sergiu-Ioan, Ionescu Costin, Bulbuc Ionut, Bordei Petru, Obada Bogdan, Voinea Felix, Gheorghe Emma, Iliescu Madalina Gabriela

机构信息

Department of Anatomy and Histology, Faculty of Medicine, 'Ovidius' University of Constanta, 900527 Constanta, Romania.

Department of Gastroenterology, Clinical County Hospital of Constanta, 900591 Constanta, Romania.

出版信息

Exp Ther Med. 2021 Oct;22(4):1192. doi: 10.3892/etm.2021.10626. Epub 2021 Aug 17.

DOI:10.3892/etm.2021.10626
PMID:34475982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8406812/
Abstract

The aim of the present study conducted on the lumbar spine was to confirm that the pronounced decrease in resistance in the system is a phenomenon that can be eminently affected by the adaptive changes that occur at the level of the intervertebral disc at axial mechanical stresses. The biomechanical trial was carried out on 11 lumbar segments L1-L5, gathered from adult human cadavers. The dissection considered the complete keeping of all bone, disc, articulated and ligamentous components in their anatomical position. All 11 samples were frozen 24 h prior to the performance of the biomechanical measurement. The specimens were placed in the testing device, their placement being conditioned by the estimated dimensional values. Thus, to calculate the load and axial resistance, the models were placed vertically, central between the test machine ferries. The testing was carried out by applying variable forces and displacement supervision. The displacement interval was represented by a segment of 0-10 mm with surveillance every 2 mm. Mobility in the sagittal plane (flexion earlier in our case) was much higher than that in the frontal plane, obviously limiting mobility via the intervertebral disc and articular complex through the presence of arches. Statistical analysis demonstrated the lack of any correlation values between the two types of movements (R=0.005507), underlining the absence of any prediction elements. A noteworthy aspect is that the correlations appeared low, statistically insignificant, even within the same movement in the sagittal plane between the two levels, L1-L3 and L3-L5 (R=0.610427), which may lead to the possibility of the emergence of significant differences in mobility between respective levels. The behavior type of the monitored specimens and the results obtained allowed the mapping of objective parallelism between the values obtained and the behavior of the lumbar vertebral segment.

摘要

本项针对腰椎开展的研究旨在确认,系统中阻力的显著降低是一种可受轴向机械应力作用下椎间盘层面发生的适应性变化显著影响的现象。对取自成年人体尸体的11个L1 - L5腰椎节段进行了生物力学试验。解剖过程中,所有骨骼、椎间盘、关节和韧带成分均保持在其解剖位置。在进行生物力学测量前24小时,将所有11个样本冷冻。将标本放置在测试装置中,其放置取决于估计的尺寸值。因此,为了计算负荷和轴向阻力,将模型垂直放置在试验机托架之间的中心位置。通过施加可变力并进行位移监测来进行测试。位移区间为0 - 10毫米,每2毫米进行一次监测。矢状面(在我们的案例中为前屈)的活动度远高于额状面,显然,由于存在椎弓,椎间盘和关节复合体限制了活动度。统计分析表明,两种运动类型之间不存在任何相关值(R = 0.005507),这突出表明不存在任何预测因素。一个值得注意的方面是,即使在矢状面内同一运动的L1 - L3和L3 - L5两个水平之间,相关性也很低,在统计学上不显著(R = 0.610427),这可能导致各水平之间活动度出现显著差异的可能性。所监测标本的行为类型以及获得的结果使得能够描绘出所获数值与腰椎节段行为之间的客观平行关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/cc13bc9e2bc3/etm-22-04-10626-g08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/c0d33dce5313/etm-22-04-10626-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/9e12ec7270ba/etm-22-04-10626-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/a51df59693e2/etm-22-04-10626-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/5e1daff12a3c/etm-22-04-10626-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/dcea94309216/etm-22-04-10626-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/450a44f51834/etm-22-04-10626-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/995a03d8fe86/etm-22-04-10626-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/964369bfae48/etm-22-04-10626-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/cc13bc9e2bc3/etm-22-04-10626-g08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/c0d33dce5313/etm-22-04-10626-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/9e12ec7270ba/etm-22-04-10626-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/a51df59693e2/etm-22-04-10626-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/5e1daff12a3c/etm-22-04-10626-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/dcea94309216/etm-22-04-10626-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/450a44f51834/etm-22-04-10626-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/995a03d8fe86/etm-22-04-10626-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/964369bfae48/etm-22-04-10626-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f6/8406812/cc13bc9e2bc3/etm-22-04-10626-g08.jpg

相似文献

1
Axial and para-axial loading response evaluation on human cadaver-harvested lumbar vertebral blocks: experiment with possible clinical implications for clinical practice.人体尸体腰椎椎体块的轴向和旁轴向加载响应评估:对临床实践具有潜在临床意义的实验
Exp Ther Med. 2021 Oct;22(4):1192. doi: 10.3892/etm.2021.10626. Epub 2021 Aug 17.
2
Biomechanical Effect of L -L Intervertebral Disc Degeneration on the Lower Lumbar Spine: A Finite Element Study.L-L型椎间盘退变对下腰椎的生物力学影响:一项有限元研究
Orthop Surg. 2020 Jun;12(3):917-930. doi: 10.1111/os.12703. Epub 2020 May 31.
3
The biomechanical effects of spondylolysis and its treatment.椎弓根峡部裂及其治疗的生物力学效应
Spine (Phila Pa 1976). 2003 Feb 1;28(3):235-8. doi: 10.1097/01.BRS.0000042226.59713.0E.
4
The Impact of Complex Loadings on the Structure of the L2-L3 Intervertebral Disc in a Sheep Spine Cadaver Model: A Biomechanical and Histological Evaluation.复杂载荷对羊脊柱尸体模型中L2-L3椎间盘结构的影响:生物力学和组织学评估
Cureus. 2024 Jan 9;16(1):e51941. doi: 10.7759/cureus.51941. eCollection 2024 Jan.
5
Precision measurement of disc height, vertebral height and sagittal plane displacement from lateral radiographic views of the lumbar spine.从腰椎侧位X线片精确测量椎间盘高度、椎体高度和矢状面位移。
Clin Biomech (Bristol). 1997;12 Suppl 1:S1-S63. doi: 10.1016/s0268-0033(96)00067-8.
6
Transforaminal lumbar interbody fusion: the effect of various instrumentation techniques on the flexibility of the lumbar spine.经椎间孔腰椎椎间融合术:各种内固定技术对腰椎灵活性的影响。
Spine (Phila Pa 1976). 2004 Feb 15;29(4):E65-70. doi: 10.1097/01.brs.0000113034.74567.86.
7
[Anatomical background of low back pain: variability and degeneration of the lumbar spinal canal and intervertebral disc].[腰痛的解剖学背景:腰椎管和椎间盘的变异性与退变]
Schmerz. 2001 Dec;15(6):418-24. doi: 10.1007/s004820100026.
8
Test-retest repeatability of lumbar sagittal alignment and disc height measurements with or without axial loading: a computed tomography study.腰椎矢状面排列及椎间盘高度测量在有无轴向负荷情况下的重测重复性:一项计算机断层扫描研究
J Spinal Disord Tech. 2011 Apr;24(2):93-8. doi: 10.1097/BSD.0b013e3181dd611f.
9
The relationship between disc degeneration and flexibility of the lumbar spine.椎间盘退变与腰椎灵活性之间的关系。
Spine J. 2001 Jan-Feb;1(1):47-56. doi: 10.1016/s1529-9430(01)00006-7.
10
Lumbar facet joint and intervertebral disc loading during simulated pelvic obliquity.模拟骨盆倾斜时腰椎小关节和椎间盘的负荷。
Spine J. 2013 Nov;13(11):1581-9. doi: 10.1016/j.spinee.2013.04.011. Epub 2013 May 21.

引用本文的文献

1
Prolotherapy as a Regenerative Treatment in the Management of Chronic Low Back Pain: A Systematic Review.注射增殖疗法作为慢性下腰痛治疗中的一种再生疗法:一项系统评价
Medicina (Kaunas). 2025 Sep 2;61(9):1588. doi: 10.3390/medicina61091588.
2
An Assessment of Behavioral Risk Factors in Oncology Patients.肿瘤患者行为风险因素评估。
Nutrients. 2024 Aug 2;16(15):2527. doi: 10.3390/nu16152527.
3
Biomechanical comparative analysis of conventional pedicle screws and cortical bone trajectory fixation in the lumbar spine: An in vitro and finite element study.

本文引用的文献

1
Current Pharmacological Treatment of Painful Diabetic Neuropathy: A Narrative Review.疼痛性糖尿病周围神经病变的当前药物治疗:叙事性综述。
Medicina (Kaunas). 2020 Jan 9;56(1):25. doi: 10.3390/medicina56010025.
2
Clinical presentation of a patient with cutis laxa with systemic involvement: a case report.一名患有全身性累及的皮肤松弛症患者的临床表现:病例报告
Rom J Morphol Embryol. 2015;56(3):1205-10.
3
Sagittal plane motion in the human lumbar spine: comparison of the in vitro quasistatic neutral zone and dynamic motion parameters.
腰椎传统椎弓根螺钉与皮质骨轨迹固定的生物力学对比分析:一项体外和有限元研究。
Front Bioeng Biotechnol. 2023 Jan 19;11:1060059. doi: 10.3389/fbioe.2023.1060059. eCollection 2023.
人体腰椎矢状面运动:体外准静态中立区与动态运动参数的比较
Clin Biomech (Bristol). 2006 Nov;21(9):914-9. doi: 10.1016/j.clinbiomech.2006.04.009. Epub 2006 Jun 8.
4
Degenerative mechanics of the lumbar spine.腰椎的退变力学
Spine J. 2004 Nov-Dec;4(6 Suppl):202S-208S. doi: 10.1016/j.spinee.2004.07.013.
5
Does long-term compressive loading on the intervertebral disc cause degeneration?长期对椎间盘施加压缩负荷会导致退变吗?
Spine (Phila Pa 1976). 2000 Dec 1;25(23):2993-3004. doi: 10.1097/00007632-200012010-00006.
6
Biomechanical behaviour in vitro of the spine and lumbosacral junction.脊柱及腰骶关节的体外生物力学行为
Surg Radiol Anat. 1999;21(6):377-81. doi: 10.1007/BF01631345.
7
Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition.人体纤维环的压缩力学性能及其与生化成分的关系。
Spine (Phila Pa 1976). 1994 Jan 15;19(2):212-21. doi: 10.1097/00007632-199401001-00017.
8
The relationship of degeneration of the intervertebral disc to mechanical loading conditions on lumbar vertebrae.椎间盘退变与腰椎机械负荷条件之间的关系。
Spine (Phila Pa 1976). 1986 Sep;11(7):726-31. doi: 10.1097/00007632-198609000-00012.
9
Mechanical behavior of the human lumbar spine. II. Fatigue strength during dynamic compressive loading.人体腰椎的力学行为。II. 动态压缩载荷下的疲劳强度。
J Orthop Res. 1987;5(4):479-87. doi: 10.1002/jor.1100050403.
10
Mechanical properties of human lumbar spine motion segments. Influence of age, sex, disc level, and degeneration.人体腰椎运动节段的力学特性。年龄、性别、椎间盘节段及退变的影响。
Spine (Phila Pa 1976). 1979 Jan-Feb;4(1):1-8. doi: 10.1097/00007632-197901000-00001.