Dhuvad Jigar M, Mehta Deval
Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Ahmedabad, Gujarat, India.
Department of Oral and Maxillofacial Surgery, College of Dental Science and Research Centre, Ahmedabad, Gujarat, India.
Natl J Maxillofac Surg. 2021 May-Aug;12(2):181-187. doi: 10.4103/njms.NJMS_12_19. Epub 2021 Jul 15.
This aimed to evaluate a new bone formation and to provide a single-stage treatment, i.e., extraction of tooth followed by autogenous dentin demineralized (ADDM) graft in the same extraction socket (ES) - for adult patients who require tooth extraction.
Two hundred teeth extractions were performed to investigate the efficacy of ADDM graft in the formation of new bone. After demineralization of dentin graft parameters such as exposure of graft, any signs of infections/pus/exudates, pain, and bone density were evaluated.
On follow-up, exposure of graft was recorded in five sockets at 1 month and infection was recorded in four sockets. Pain was significantly high at postoperative day 1 and least with 3 and 6 months. There was a highly significant bone formation ( < 0.01, 0.05) in the ES group at various time intervals, while there were no significant differences in the adjacent bone group.
Using ADDM graft in providing a single-stage treatment plan, i.e., extraction of tooth followed by autogenous demineralized dentin graft in the same ES in adult patients - is an alternative for the immediate reconstruction of alveolar bone defects to facilitate the future prosthesis. It also saves the cost of other graft materials which are commercially available in market for the patient and also reduces the infective dental waste globally.
本研究旨在评估一种新的骨形成方法，并提供一种单阶段治疗方案，即对于需要拔牙的成年患者，在同一拔牙窝（ES）内先拔牙，随后植入自体脱矿牙本质（ADDM）移植物。
进行了200例拔牙手术，以研究ADDM移植物在新骨形成中的疗效。对牙本质移植物进行脱矿处理后，评估移植物暴露情况、感染/脓液/渗出物迹象、疼痛以及骨密度等参数。
随访发现，1个月时5个牙槽窝记录到移植物暴露，4个牙槽窝记录到感染。术后第1天疼痛明显较高，3个月和6个月时疼痛最少。ES组在不同时间间隔均有高度显著的骨形成（<0.01，0.05），而相邻骨组则无显著差异。
对于成年患者，在同一ES内采用ADDM移植物提供单阶段治疗方案，即先拔牙，随后植入自体脱矿牙本质移植物，是立即重建牙槽骨缺损以利于未来修复体的一种替代方法。它还为患者节省了市场上其他可商购移植物材料的成本，并减少了全球范围内的感染性牙科废物。
