Ewnetu Tarekegn Gebrekidan, Derseh Gezie Lemma, Yemanu Birhan Tilahun, Ewnetu Frew
Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Patient Relat Outcome Meas. 2021 Aug 28;12:279-290. doi: 10.2147/PROM.S322421. eCollection 2021.
Chronic heart failure is one of the most important public health concerns in the industrialized and developing world having increasing prevalence. Measuring quality of life using rigorous statistical methods may be helpful to provide input for decision-makers and the development of guidelines. This study aimed to assess health-related quality of life and associated factors among heart failure patients attending the University of Gondar Specialized Hospital.
A cross-sectional study was employed to select 469 heart failure patients who have follow-up at the University of Gondar Specialized Hospital consecutively from March 01 to 30, 2020. Data were entered to Epi Info 7 and exported to STATA version 15 for further statistical analysis. The quality-of-life domains were measured with World Health Organization Quality of Life BREF. Structural equation modeling was employed to estimate the relationships among exogenous, mediating, and endogenous variables simultaneously.
Chronic heart failure patients had a significantly lower mean score in physical health domain (31.70 mean score), environmental health domain (38.35 mean score), and in overall quality of life domain (41.61 mean score) moderate in social relation domain (46.22 mean score), and in psychological health domain (50.21 mean score) of health-related quality of life (p-value <0.0001). Age had a direct positive effect on health-related quality of life. Residency also had a direct negative effect on both physical and environmental health-related quality of life domain. Duration of heart failure had a direct negative effect on psychological health.
The finding of this study indicated that poor health-related quality of life in the physical health domain, moderately poor in overall health-related quality of life, and moderate health-related quality of life in the psychological health domain among Chronic heart failure patients. Age, residence, marital status, income, and duration of HF were significantly associated factors for quality of life among HF patients.
慢性心力衰竭是工业化国家和发展中国家最重要的公共卫生问题之一,其患病率不断上升。使用严格的统计方法衡量生活质量可能有助于为决策者提供信息并制定指南。本研究旨在评估贡德尔大学专科医院心力衰竭患者的健康相关生活质量及相关因素。
采用横断面研究,选取2020年3月1日至30日在贡德尔大学专科医院连续随访的469例心力衰竭患者。数据录入Epi Info 7并导出到STATA 15版本进行进一步统计分析。生活质量领域采用世界卫生组织生活质量简表进行测量。采用结构方程模型同时估计外生、中介和内生变量之间的关系。
慢性心力衰竭患者在健康相关生活质量的身体健康领域(平均得分31.70)、环境健康领域(平均得分38.35)和总体生活质量领域(平均得分41.61)得分显著较低,社会关系领域(平均得分46.22)得分中等,心理健康领域(平均得分50.21)得分中等(p值<0.0001)。年龄对健康相关生活质量有直接正向影响。居住地对身体健康和环境健康相关生活质量领域也有直接负向影响。心力衰竭病程对心理健康有直接负向影响。
本研究结果表明,慢性心力衰竭患者在身体健康领域的健康相关生活质量较差,总体健康相关生活质量中等较差,心理健康领域的健康相关生活质量中等。年龄、居住地、婚姻状况、收入和心力衰竭病程是心力衰竭患者生活质量的显著相关因素。