Key Laboratory of Ecology and Environment in Minority Areas (Minzu University of China), National Ethnic Affairs Commission, Beijing, 100081, China; College of Life and Environmental Sciences, Minzu University of China, Beijing, 100081, China.
Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Guizhou University), Ministry of Education, Guiyang, 550025, China; School of Liquor and Food Engineering, Guizhou University, Guiyang, 550025, China.
J Ethnopharmacol. 2022 Jan 10;282:114572. doi: 10.1016/j.jep.2021.114572. Epub 2021 Sep 3.
Acer truncatum Bunge is a multifunctional plant in northern China. It has traditionally been used to prevent cardiovascular and cerebrovascular diseases and treat skin trauma by different linguistic groups including Mongolian, Tibetan, and Korean. Although research has verified that A. truncatum contains a variety of active ingredients, especially nervonic acid, an important component in delaying brain aging, to date no review has been made to compile its traditional use, phytochemistry, and pharmacology.
This review aimed to update the traditional uses, phytochemistry, and pharmacology of A. truncatum, which expect to provide theoretical support for the future utilization as well as highlight the further investigation of this important plant.
The ethnobotanical, phytochemical, and pharmacological information related to A. truncatum from 1949 to March 2021 were collated by surveying the traditional medicinal books and ethnomedicinal publications and searching the online databases including Google Scholar, Sci Finder, Web of Science, Springer Link, PubMed, Wiley, China National Knowledge Infrastructure (CNKI), Baidu Scholar, and Wan Fang Database.
A. truncatum has traditionally been used for medicinal, edible and ornamental purposes in northern China for many centuries. Different parts of the plant including leaves, fruits and bark, are mainly used as herbal medicine to treat hyperpiesia, hyperlipidemia, bruises, back pain, etc. A total of 288 compounds in A. truncatum, including polyphenols, organic acids or lipids, and biological volatile organic compounds were isolated or identified by phytochemical studies. Pharmacological research showed that A. truncatum has various bioactivities such as acetylcholinesterase inhibition, antibacterial, antioxidant, antitumor, and fatty acid synthase inhibition effects.
A. truncatum has been used as a traditional herbal medicine for centuries in northern China. Polyphenols, organic acids, lipids and other compounds were isolated or identified from different parts of the plant. Most of the pharmacological activities of A. truncatum have been reported, which showed its potential in the development of new drugs or nutraceuticals. However, detailed information on the molecular mechanisms, metabolic activity, and toxicology of active components is limited. Further comprehensive research to evaluate the medicinal properties of A. truncatum will be necessary.
中国北方的复叶槭是一种多功能植物。不同的语言群体，包括蒙古族、藏族和朝鲜族，都将其传统上用于预防心脑血管疾病和治疗皮肤创伤。尽管研究已经证实，复叶槭含有多种活性成分，特别是神经酸，这是延缓大脑衰老的重要成分，但迄今为止，还没有对其传统用途、植物化学和药理学进行综述。
本综述旨在更新复叶槭的传统用途、植物化学和药理学，以期为未来的利用提供理论支持，并强调对这种重要植物的进一步研究。
通过查阅传统医学书籍和民族医学出版物，并在线检索 Google Scholar、Sci Finder、Web of Science、Springer Link、PubMed、Wiley、中国知网（CNKI）、百度学术和万方数据库等在线数据库，收集了 1949 年至 2021 年 3 月与复叶槭相关的民族植物学、植物化学和药理学信息。
复叶槭在中国北方被传统地用于药用、食用和观赏用途，已有数个世纪的历史。植物的不同部位，包括叶子、果实和树皮，主要用作草药，用于治疗高血压、高血脂、瘀伤、背痛等。通过植物化学研究，从复叶槭中分离或鉴定出 288 种化合物，包括多酚、有机酸或脂质和生物挥发性有机化合物。药理研究表明，复叶槭具有乙酰胆碱酯酶抑制、抗菌、抗氧化、抗肿瘤和脂肪酸合酶抑制等多种生物活性。
复叶槭在中国北方已被用作传统草药数百年。从植物的不同部位分离或鉴定出多酚、有机酸、脂质等化合物。复叶槭的大多数药理活性已被报道，这表明其在开发新药或营养保健品方面具有潜力。然而，关于活性成分的分子机制、代谢活性和毒理学的详细信息有限。需要进一步进行全面的研究来评估复叶槭的药用特性。
