College of Food Science and Engineering, Jilin University, Changchun, China.
Crit Rev Food Sci Nutr. 2023;63(14):2216-2230. doi: 10.1080/10408398.2021.1972280. Epub 2021 Sep 7.
As a notorious food-borne pathogen, can readily cause diseases in humans via contaminated food. Biofilm formation on various surfaces can increase the capacity of viable cells for self-protection due to the stubborn structure of the biofilm matrix. Increased disease risk and economic losses caused by biofilm contamination in the food industry necessitate the urgent development of effective strategies for the inhibition and removal of biofilms. Natural products have been extensively used as important sources of "eco-friendly" antibiofilm agents to avoid the side effects of conventional strategies on human health and the environment. This review discusses biofilm formation of in food industries and focuses on providing an overview of potential promising target-oriented natural products and their mechanisms of biofilm inhibition or removal. Hoping to provide valuable information of attractive research targets or potential undeveloped targets to screen potent natural anti-biofilm agents in food industries.
作为一种臭名昭著的食源性病原体， 可以通过污染的食物轻易地在人类中引发疾病。生物膜在各种表面上的形成可以增加存活细胞的自我保护能力，因为生物膜基质的结构非常顽固。食品工业中生物膜污染导致的疾病风险增加和经济损失，需要迫切开发有效的抑制和去除 生物膜的策略。天然产物已被广泛用作“环保型”抗生物膜剂的重要来源，以避免传统策略对人类健康和环境的副作用。本综述讨论了 在食品工业中的生物膜形成，并重点介绍了有希望的靶向天然产物及其抑制或去除 生物膜的机制。希望为筛选食品工业中具有潜力的天然抗生物膜剂提供有吸引力的研究目标或潜在未开发目标的有价值信息。
