Irvine Nathaniel J, Wiles Brittany L
Family Medicine, Naval Hospital Jacksonville, Jacksonville, USA.
Cureus. 2021 Aug 3;13(8):e16858. doi: 10.7759/cureus.16858. eCollection 2021 Aug.
Since late 2019, the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus2(SARS-CoV-2), has killed over three million people. More than 600,000 of these deaths have occurred in the United States alone. While advances in the treatment of COVID-19 have been made, the advent of highly effective vaccines against this coronavirus variant has given hope that the end of the pandemic may be near. Unfortunately, resistance towards vaccination remains a barrier to virus eradication both in the United States and globally. The driving factor for much of this opposition is the concern over potential adverse reactions from the vaccines against SARS-CoV-2. In order to combat this, it is imperative that vaccine side effects and their corresponding clinical course are clearly described. This report details the case of a female patient who developed acral petechiae, desquamation of the fingers, and a facial rash that occurred shortly after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine.
自2019年末以来，由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019冠状病毒病（COVID-19）大流行已导致超过300万人死亡。仅在美国，就有超过60万人死于该病。虽然在COVID-19治疗方面取得了进展，但针对这种冠状病毒变种的高效疫苗的出现，让人们看到了大流行可能即将结束的希望。不幸的是，在美国和全球范围内，对疫苗接种的抵触仍然是根除病毒的障碍。这种反对情绪的主要驱动因素是对SARS-CoV-2疫苗潜在不良反应的担忧。为了解决这个问题，必须清楚地描述疫苗的副作用及其相应的临床过程。本报告详细介绍了一名女性患者的病例，该患者在接种第二剂辉瑞-生物科技公司的COVID-19疫苗后不久，出现了手足瘀点、手指脱皮和面部皮疹。
