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乳制品与伊朗成年人中大量心理障碍之间的关联。

The association between dairy products and psychological disorders in a large sample of Iranian adults.

机构信息

Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Nutr Neurosci. 2022 Nov;25(11):2379-2389. doi: 10.1080/1028415X.2021.1969065. Epub 2021 Sep 11.

Abstract

BACKGROUND

Dairy products contain certain nutrients that are useful in mental disorders. This study aimed to assess the associations between dairy products and psychological disorders in a large sample of Iran, a Middle Eastern country.

METHODS

This cross-sectional study was undertaken on 7387 adults. Data on dietary intakes were obtained using a validated Food Frequency Questionnaire. Psychological health was assessed by the Iranian validated version of depression, anxiety, and stress scale 21. Multivariable logistic regression analysis was performed to analyze the association between dairy intake and psychological disorders.

RESULTS

After adjustment for potential confounders, total milk consumption (OR for the highest vs. lowest tertile: 0.73, 0.58-0.92) and total yogurt consumption (0.78, 0.62-0.97) were associated with decreased odds of depression. An inverse relationship was found between total dairy (0.73, 95% CI 0.590.91), total milk (0.72; 0.58-0.88), kashk (0.79, 0.65-0.96), and yogurt drink (0.80, 95% CI 0.65-0.98) consumption and anxiety symptoms. Higher intake of cheese was related to greater odds of stress (1.52, 1.02-2.26). No association was found between the consumption of high-fat dairy, low-fat dairy, low-fat milk, low-fat yogurt, high-fat yogurt, cheese, kashk, yogurt drink, and depression. Also, there is no association between dairy products and stress symptoms. This association was significant among men and women and high-fat and low-fat products in the total adjusted stratified analysis models.

CONCLUSIONS

Findings of this study revealed that both high-fat and low-fat dairy products are associated with a reduced prevalence of psychological disorders. Still, more prospective studies are required to confirm these associations.

摘要

背景

乳制品含有某些对精神疾病有益的营养物质。本研究旨在评估乳制品与中东国家伊朗的大量人群中心理障碍之间的关联。

方法

这项横断面研究共纳入 7387 名成年人。使用经过验证的食物频率问卷获取饮食摄入量数据。采用伊朗版抑郁、焦虑和压力量表 21 评估心理健康状况。采用多变量逻辑回归分析评估乳制品摄入量与心理障碍之间的关联。

结果

调整潜在混杂因素后,总牛奶摄入量(最高与最低三分位组的比值比:0.73,0.58-0.92)和总酸奶摄入量(0.78,0.62-0.97)与抑郁几率降低相关。总乳制品(0.73,95%置信区间 0.59-0.91)、总牛奶(0.72;0.58-0.88)、kashk(0.79,0.65-0.96)和酸奶饮料(0.80,95%置信区间 0.65-0.98)摄入量与焦虑症状呈负相关。较高的奶酪摄入量与更大的压力几率相关(1.52,1.02-2.26)。高脂肪乳制品、低脂肪乳制品、低脂牛奶、低脂酸奶、高脂酸奶、奶酪、kashk、酸奶饮料、与抑郁之间无关联。同样,乳制品与压力症状之间也无关联。在总调整分层分析模型中,这种关联在男性和女性以及高脂肪和低脂肪产品中均具有统计学意义。

结论

本研究结果表明,高脂肪和低脂肪乳制品均与心理障碍的患病率降低有关。但仍需要更多的前瞻性研究来证实这些关联。

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