评估中央视网膜动脉阻塞患者的红细胞分布宽度、血小板/淋巴细胞比值、全身免疫炎症指数和中性粒细胞/淋巴细胞比值。
Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion.
机构信息
Tayfur Ata Sokmen Faculty of Medicine, Department of Ophthalmology, Mustafa Kemal University, Hatay, Turkey.
Department of Ophthalmology, Sakarya Training and Research Hospital, Sakarya, Turkey.
出版信息
Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1940-1944. doi: 10.1080/09273948.2021.1976219. Epub 2021 Sep 15.
PURPOSE
To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).
METHODS
A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated.
RESULTS
RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p < .001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p = .008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p = .008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively.
CONCLUSION
RDW seems superior to other inflammatory indices to predict CRAO.
目的
评估中央视网膜动脉阻塞（CRAO）患者全血细胞计数（CBC）衍生的炎症指标。
方法
共纳入 42 例 CRAO 患者（CRAO 组）和 42 例年龄和性别匹配的无 CRAO 患者（对照组）。检测了 CBC 参数，包括红细胞分布宽度（RDW）水平。计算了血小板/淋巴细胞比值（PLR）、全身免疫炎症指数（SII）和中性粒细胞/淋巴细胞比值（NLR）。
结果
CRAO 组的 RDW、PLR、SII 和 NLR 值明显高于对照组[15.2±1.47%比 13.96±1.13%（p<0.001），127.94±48.21 比 101.16±24.84（p=0.008），667.11±357.84 比 493.44±207.07（p=0.008），2.70±1.27 比 2.13±0.83（p=0.018）]。多变量分析显示，只有 RDW 是 CRAO 的独立预测因素（OR 2.317，p<0.001）。在 ROC 分析中，RDW、PLR、SII 和 NLR 预测 CRAO 的曲线下面积分别为 0.761、0.685、0.622 和 0.618。
结论
RDW 似乎优于其他炎症指标，可预测 CRAO。
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