Centre de Recherche du CHU de Québec - Université Laval, Axe Neurosciences, Québec, QC, Canada; Département de Psychiatrie & Neurosciences, Université Laval, Québec, QC, Canada.
Neurodegenerative Diseases Group, Montreal Neurological Institute-Hospital, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.
Parkinsonism Relat Disord. 2021 Oct;91:66-76. doi: 10.1016/j.parkreldis.2021.08.018. Epub 2021 Sep 1.
The COVID-19 pandemic has necessitated the social isolation of the population and the rapid implementation of remote care for patients with neurodegenerative diseases. The objective of this study was to explore the perceived impact of confinement in patients with Parkinson's disease and document the effects of gender and living environment.
We recruited two cohorts from the Canadian provinces of Québec and Alberta, which differed in the dynamics of COVID-19 spreading at the time of the study, and administered a questionnaire on the perceived effects of confinement on daily living and disease management.
The data reveals that approximately half of the patients experienced a change in one or more clinical symptoms, with differences observed between gender (e.g. day-to-day changes in slowness in men, aggravated headaches in women) and geographic location (e.g. increased depression in Alberta but reduced sleep quality in Québec). Furthermore, participants identifying as women or living in Alberta implemented more frequently home or online exercise. Lastly, high levels of satisfaction with phone or video consultations did not translate into a sustained interest to pursue this mode of healthcare.
This study suggests that COVID-19-related confinement affected Parkinson's disease manifestation and management. Patients also reported varying levels of interest to continue remote care. A number of differences reported in our study were seemingly related to gender and living environment.
COVID-19 大流行迫使人们进行社交隔离，并迅速为神经退行性疾病患者实施远程护理。本研究旨在探讨禁闭对帕金森病患者的感知影响，并记录性别和生活环境的影响。
我们从加拿大魁北克省和艾伯塔省招募了两个队列，这两个队列在研究时 COVID-19 传播的动态不同，并就禁闭对日常生活和疾病管理的感知影响进行了问卷调查。
数据显示，大约一半的患者经历了一个或多个临床症状的变化，性别（例如男性日常活动变缓慢，女性头痛加剧）和地理位置（例如艾伯塔省抑郁增加，魁北克省睡眠质量下降）存在差异。此外，自认为是女性或居住在艾伯塔省的参与者更频繁地在家中或在线进行锻炼。最后，对电话或视频咨询的高度满意度并没有转化为持续关注这种医疗保健模式的兴趣。
本研究表明，与 COVID-19 相关的禁闭影响了帕金森病的表现和管理。患者也报告了对继续远程护理的不同程度的兴趣。我们研究中报告的一些差异似乎与性别和生活环境有关。
