Department of Rehabilitation and Health Services, University of North Texas, Denton, TX, United States.
David Geffen School of Medicine, UCLA, Department of Neurology, Los Angeles, CA, United States; PADRECC, West Los Angeles, Veterans Administration, Los Angeles, CA, United States.
Int Rev Neurobiol. 2022;165:197-227. doi: 10.1016/bs.irn.2022.03.003. Epub 2022 Apr 23.
People living with Parkinson Disease (PwP) have been at risk for the negative effects of loneliness even before the Coronavirus Disease 2019 (Covid-19) pandemic. Despite some similarities with previous outbreaks, the Covid-19 pandemic is significantly more wide-spread, long-lasting, and deadly, which likely means demonstrably more negative mental health issues. Although PwP are not any more likely to contract Covid-19 than those without, the indirect negative sequelae of isolation, loneliness, mental health issues, and worsening motor and non-motor features remains to be fully realized. Loneliness is not an isolated problem; the preliminary evidence indicates that loneliness associated with the Covid-19 restrictions has dramatically increased in nearly all countries around the world.
帕金森病患者（PwP）即使在 2019 年冠状病毒病（COVID-19）大流行之前，也一直面临孤独的负面影响的风险。尽管与以前的疫情有一些相似之处，但 COVID-19 大流行的范围更广、持续时间更长、致命性更高，这可能意味着明显更多的负面心理健康问题。尽管帕金森病患者感染 COVID-19 的可能性并不比其他人高，但隔离、孤独、心理健康问题以及运动和非运动特征恶化的间接负面后果仍有待充分认识。孤独不是一个孤立的问题；初步证据表明，与 COVID-19 限制相关的孤独感在世界几乎所有国家都急剧增加。
