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癌症儿童恶心呕吐量表的制定。

Developing the Nausea and Vomiting Thermometer Scale in children with cancer.

机构信息

Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.

Department of Pediatric Nursing, Faculty of Nursing, Dokuz Eylül University, İzmir, Turkey.

出版信息

Turk J Med Sci. 2022 Feb;52(1):166-174. doi: 10.3906/sag-2005-88. Epub 2022 Feb 22.

DOI:10.3906/sag-2005-88
PMID:34544217
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10734878/
Abstract

BACKGROUND

This study aimed to develop the Nausea and Vomiting Thermometer Scale (NVTS) in children with cancer.

METHODS

This methodological study was conducted on 250 children with cancer at the research and training university hospital in Turkey between September 2019 and January 2020. The t-test, the ROC analysis, the Diagnostic index, and the Youden index were used for determining the scale of the cutting point. The regression analysis, the intra-class correlation coefficient, and the BlandAltman analysis were used for the data analysis.

RESULTS

The scale-level content validity index was .94, which was coherent. As a result of the ROC analysis, the cut-off point was determined as three points. The NVTS showed good reliability, with an intra-class correlation coefficient of .99. In the linear regression analysis, a model was created for chemotherapy drugs, nausea and vomiting type, vomiting status, and the number of children with cancer who vomited explained 44.9% of their nausea and vomiting status. The results of the Bland-Altman analysis showed that the correlation coefficient between the differences and the means was insignificant.

摘要

背景

本研究旨在为癌症患儿开发恶心和呕吐温度计量表（NVTS）。

方法

本方法学研究于 2019 年 9 月至 2020 年 1 月在土耳其的一所研究和培训大学医院对 250 名癌症患儿进行。使用 t 检验、ROC 分析、诊断指数和 Youden 指数来确定截断点的量表。使用回归分析、组内相关系数和 BlandAltman 分析进行数据分析。

结果

量表级内容效度指数为.94，具有一致性。ROC 分析的结果确定截断点为 3 分。NVTS 显示出良好的可靠性，组内相关系数为.99。在线性回归分析中，为化疗药物、恶心和呕吐类型、呕吐状态以及呕吐的癌症患儿数量创建了一个模型，解释了 44.9%的恶心和呕吐状态。Bland-Altman 分析的结果表明，差异与平均值之间的相关系数无显著性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1f/10734878/e70d0dc3d16e/turkjmedsci-52-1-166f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1f/10734878/ab7fcb5f5b42/turkjmedsci-52-1-166f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1f/10734878/e3c8172bcd02/turkjmedsci-52-1-166f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1f/10734878/e70d0dc3d16e/turkjmedsci-52-1-166f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1f/10734878/ab7fcb5f5b42/turkjmedsci-52-1-166f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1f/10734878/e3c8172bcd02/turkjmedsci-52-1-166f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1f/10734878/e70d0dc3d16e/turkjmedsci-52-1-166f3.jpg

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本文引用的文献

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Symptoms in Children Receiving Treatment for Cancer-Part I: Fatigue, Sleep Disturbance, and Nausea/Vomiting.接受癌症治疗的儿童的症状——第一部分：疲劳、睡眠障碍和恶心/呕吐
J Pediatr Oncol Nurs. 2019 Jul/Aug;36(4):244-261. doi: 10.1177/1043454219849576.
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Mind-Body Therapies in Childhood Cancer.儿童癌症的身心疗法。
Curr Psychiatry Rep. 2018 Jul 21;20(8):58. doi: 10.1007/s11920-018-0927-6.
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Validity and Reliability of the Turkish Version of the Adapted Rhodes Index of Nausea and Vomiting for Pediatrics by Child (ARINVc) and by Parent (ARINVp).
儿童版（ARINVc）和家长版（ARINVp）的土耳其语改编版《儿科恶心呕吐罗兹指数》的有效性和可靠性。
J Pediatr Oncol Nurs. 2018 Sep/Oct;35(5):353-360. doi: 10.1177/1043454218765173. Epub 2018 Apr 12.
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Pragmatic Applications of RE-AIM for Health Care Initiatives in Community and Clinical Settings.在社区和临床环境中，RE-AIM 在医疗保健计划中的实用应用。
Prev Chronic Dis. 2018 Jan 4;15:E02. doi: 10.5888/pcd15.170271.
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Symptom Clusters in Children and Adolescents with Cancer.患有癌症的儿童和青少年的症状群
Semin Oncol Nurs. 2016 Nov;32(4):394-404. doi: 10.1016/j.soncn.2016.08.005. Epub 2016 Oct 21.
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2016 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting and of nausea and vomiting in advanced cancer patients.2016年MASCC和ESMO关于预防化疗和放疗引起的恶心呕吐以及晚期癌症患者恶心呕吐的指南更新。
Ann Oncol. 2016 Sep;27(suppl 5):v119-v133. doi: 10.1093/annonc/mdw270.
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Guideline for the Treatment of Breakthrough and the Prevention of Refractory Chemotherapy-Induced Nausea and Vomiting in Children With Cancer.儿童癌症患者突破性化疗引起的恶心和呕吐的治疗及难治性化疗引起的恶心和呕吐的预防指南。
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Biochem Med (Zagreb). 2015 Jun 5;25(2):141-51. doi: 10.11613/BM.2015.015. eCollection 2015.
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