Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, 61481, Saudi Arabia.
Department of Medical Laboratory Technology, Jazan University, Jazan, Saudi Arabia.
Virol J. 2021 Sep 20;18(1):190. doi: 10.1186/s12985-021-01660-7.
Despite the fact that the chikungunya viral infection is a neglected disease, complications such as hemorrhagic fever, arthritis, and lymphopenia remain a health concern. The aim of this study was to determine the prevalence of the chikungunya virus in the Southern Region, Saudi Arabia. Enzyme immunoassay and polymerase chain reaction have been compared between samples.
Forty samples from two southern hospitals in Saudi Arabia were collected between December 2019 and February 2020 and screened for chikungunya virus IgG antibodies and for viral RNA. Selection criteria were based on hematological parameters and rheumatological profiles such as rheumatoid factor, c-reactive protein, anti-nuclear antibody, and anti-cyclic citrullinated peptide (anti-CCP) of out-patients.
One confirmed case of chikungunya virus was detected using the ELISA test. However, no viral RNA was detected in any of the samples. This suggests that the virus is cleared rapidly in patients.
Chikungunya is a neglected viral disease in Saudi Arabia. Future work should focus on detailed investigation of this viral infection and its vectors.
尽管基孔肯雅病毒感染是一种被忽视的疾病，但出血热、关节炎和淋巴细胞减少症等并发症仍然是一个健康问题。本研究旨在确定沙特阿拉伯南部地区基孔肯雅病毒的流行情况。酶免疫测定法和聚合酶链反应已在样本之间进行了比较。
2019 年 12 月至 2020 年 2 月期间，从沙特阿拉伯的两家南部医院采集了 40 份样本，用于筛查基孔肯雅病毒 IgG 抗体和病毒 RNA。选择标准基于血液学参数和风湿学特征，如门诊患者的类风湿因子、C 反应蛋白、抗核抗体和抗环瓜氨酸肽（抗-CCP）。
使用 ELISA 试验检测到 1 例确诊的基孔肯雅病毒病例。然而，在任何样本中均未检测到病毒 RNA。这表明病毒在患者体内迅速清除。
在沙特阿拉伯，基孔肯雅热是一种被忽视的病毒性疾病。未来的工作应重点详细调查这种病毒感染及其载体。
