Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Maiduguri, PMB 1069, Maiduguri, Borno State, Nigeria.
J Vet Med Sci. 2021 Oct 31;83(11):1702-1707. doi: 10.1292/jvms.21-0144. Epub 2021 Sep 20.
Tuberculosis (TB) is a chronic inflammatory and zoonotic disease caused by Mycobacterium tuberculosis complex (MTBC) members, affecting several domestic animals, wildlife species and humans. The preliminary investigation was aimed to detect antibody against MTBC among indigenous wildlife which are free-ranged wild boar, free-ranged wild macaques and captive Asian elephants in selected areas of Selangor and elephant conservation centre in Pahang, respectively. The results indicate that MTBC serodetection rate in wild boar was 16.7% (7.3-33.5 at 95% confidence interval (CI)) using an in-house ELISA bPPD IgG and 10% (3.5-25.6 at 95% CI) by DPPVetTB assay, while the wild macaques and Asian elephant were seronegative. The univariate analysis indicates no statistically significant difference in risk factors for sex and age of wild boar but there was a significant positive correlation (P<0.05) between bovine TB in dairy cattle and wild boar seropositivity in the Sepang district.
结核病（TB）是由结核分枝杆菌复合体（MTBC）成员引起的慢性炎症性人畜共患病，影响多种家畜、野生动物和人类。初步调查旨在检测雪兰莪州选定地区的自由放养野猪、自由放养野生猕猴和圈养亚洲象以及彭亨大象保护区内的土著野生动物对 MTBC 的抗体。结果表明，使用内部 ELISA bPPD IgG 检测，野猪的 MTBC 血清检出率为 16.7%（95%置信区间（CI）为 7.3-33.5），而 DPPVetTB 检测为 10%（95% CI 为 3.5-25.6），野生猕猴和亚洲象均呈血清阴性。单因素分析表明，野猪的性别和年龄因素在统计学上没有显著差异，但在雪兰莪区，奶牛中的牛型结核与野猪的血清阳性呈显著正相关（P<0.05）。
