Chandrasekaran Santosh, Fifer Matthew, Bickel Stephan, Osborn Luke, Herrero Jose, Christie Breanne, Xu Junqian, Murphy Rory K J, Singh Sandeep, Glasser Matthew F, Collinger Jennifer L, Gaunt Robert, Mehta Ashesh D, Schwartz Andrew, Bouton Chad E
Neural Bypass and Brain Computer Interface Laboratory, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Research and Exploratory Development Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
Bioelectron Med. 2021 Sep 22;7(1):14. doi: 10.1186/s42234-021-00076-6.
Almost 100 years ago experiments involving electrically stimulating and recording from the brain and the body launched new discoveries and debates on how electricity, movement, and thoughts are related. Decades later the development of brain-computer interface technology began, which now targets a wide range of applications. Potential uses include augmentative communication for locked-in patients and restoring sensorimotor function in those who are battling disease or have suffered traumatic injury. Technical and surgical challenges still surround the development of brain-computer technology, however, before it can be widely deployed. In this review we explore these challenges, historical perspectives, and the remarkable achievements of clinical study participants who have bravely forged new paths for future beneficiaries.
近100年前，涉及对大脑和身体进行电刺激及记录的实验开启了关于电、运动和思维如何关联的新发现与辩论。几十年后，脑机接口技术开始发展，如今其目标是广泛的应用领域。潜在用途包括为闭锁综合征患者提供辅助沟通，以及恢复那些与疾病作斗争或遭受创伤性损伤者的感觉运动功能。然而，在脑机技术能够广泛应用之前，技术和手术方面的挑战仍然存在。在这篇综述中，我们探讨了这些挑战、历史观点，以及临床研究参与者所取得的卓越成就，他们勇敢地为未来的受益者开辟了新道路。
