生物电子医学：临床前的洞察与临床进展。
Bioelectronic medicine: Preclinical insights and clinical advances.
机构信息
Institute of Bioelectronic Medicine, the Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA; Elmezzi Graduate School of Molecular Medicine, Northwell Health, Manhasset, NY, USA; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
出版信息
Neuron. 2022 Nov 2;110(21):3627-3644. doi: 10.1016/j.neuron.2022.09.003. Epub 2022 Sep 28.
Abstract
The nervous system maintains homeostasis and health. Homeostatic disruptions underlying the pathobiology of many diseases can be controlled by bioelectronic devices targeting CNS and peripheral neural circuits. New insights into the regulatory functions of the nervous system and technological developments in bioelectronics drive progress in the emerging field of bioelectronic medicine. Here, we provide an overview of key aspects of preclinical research, translation, and clinical advances in bioelectronic medicine.
摘要
神经系统维持着体内平衡和健康。许多疾病的病理生物学基础是体内平衡的破坏，针对中枢神经系统和周围神经回路的生物电子设备可以控制这种破坏。对神经系统调节功能的新认识和生物电子学技术的发展推动了生物电子医学这一新兴领域的进展。在这里，我们提供了生物电子医学的临床前研究、转化和临床进展的关键方面的概述。
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