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新冠肺炎患者住院期间的创伤后应激障碍症状与睡眠质量:一项来自两个中心的观察性研究

PTSD Symptoms and Sleep Quality of COVID-19 Patients During Hospitalization: An Observational Study from Two Centers.

作者信息

Sun Luna, Yi Bin, Pan Xiao, Wu Lili, Shang Zhilei, Jia Yanpu, Tao Xiandong, Zhao Feng, Xie Weifen, Sun Zhuoer, Bai Yonghai, Liu Weizhi

机构信息

Lab for Post-Traumatic Stress Disorder, Faculty of Psychology and Mental Health, Naval Medical University, Shanghai, 200433, People's Republic of China.

The Emotion & Cognition Lab, Faculty of Psychology and Mental Health, Naval Medical University, Shanghai, 200433, People's Republic of China.

出版信息

Nat Sci Sleep. 2021 Sep 14;13:1519-1531. doi: 10.2147/NSS.S317618. eCollection 2021.

Abstract

BACKGROUND

The outbreak of COVID-19 has developed into a pandemic. Data are required that specifically address the psychological consequences in COVID-19 confirmed patients. This study mainly aimed to examine posttraumatic stress disorder (PTSD) symptoms and sleep quality among COVID-19 confirmed patients during hospitalization.

METHODS

An observational study was conducted in two designated hospitals in Wuhan, China. Data were collected from 190 patients hospitalized with laboratory-confirmed COVID-19 infection between February 10, 2020 and March 13, 2020.

RESULTS

The mean age of the 190 confirmed patients was 55.7 years (SD = 13.7), of which 96 (50.5%) were female and 88 (46.3%) had family members or acquaintances infected with COVID-19. Lymphocytopenia was presented in 62 (32.6%) patients and 25 (13.2%) patients showed oxygen desaturation. The prevalence of high PTSD symptoms was 22.6% among the 190 patients. The median time from symptom onset to first medical visit and hospitalization was 2 days (IQR, 1-5) and 16 days (IQR, 10-27), respectively. Patients' PTSD symptoms were positively related to the time from symptom onset to first medical visit ( = 0.156, < 0.05) and hospitalization ( = 0.181, < 0.01). There were significant correlations between sleep quality and PTSD symptoms ( = 0.312-0.547, < 0.01).

CONCLUSION

The prevalence of high PTSD symptoms was 22.6% among hospitalized COVID-19 patients. Early diagnosis and treatment of COVID-19 symptoms are beneficial to infected patients both physically and psychologically. With the recovery of physical symptoms, psychological intervention is desired to promote the trauma recovery in COVID-19 patients.

摘要

背景

新型冠状病毒肺炎(COVID-19)疫情已发展成为全球大流行。需要有专门针对COVID-19确诊患者心理后果的数据。本研究主要旨在调查COVID-19确诊患者住院期间的创伤后应激障碍(PTSD)症状和睡眠质量。

方法

在中国武汉的两家定点医院进行了一项观察性研究。收集了2020年2月10日至2020年3月13日期间190例实验室确诊为COVID-19感染的住院患者的数据。

结果

190例确诊患者的平均年龄为55.7岁(标准差=13.7),其中96例(50.5%)为女性,88例(46.3%)有家庭成员或熟人感染了COVID-19。62例(32.6%)患者出现淋巴细胞减少,25例(13.2%)患者出现氧饱和度下降。190例患者中PTSD症状严重的患病率为22.6%。从症状出现到首次就诊和住院的中位时间分别为2天(四分位间距,1-5)和16天(四分位间距,10-27)。患者的PTSD症状与从症状出现到首次就诊的时间(r=0.156,P<0.05)和住院时间(r=0.181,P<0.01)呈正相关。睡眠质量与PTSD症状之间存在显著相关性(r=0.312-0.547,P<0.01)。

结论

住院COVID-19患者中PTSD症状严重的患病率为22.6%。早期诊断和治疗COVID-19症状对感染患者的身体和心理都有益。随着身体症状的恢复,需要进行心理干预以促进COVID-19患者的创伤恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154c/8449687/17408c40fce4/NSS-13-1519-g0001.jpg

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