State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China; Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
Carbohydr Polym. 2021 Dec 1;273:118565. doi: 10.1016/j.carbpol.2021.118565. Epub 2021 Aug 27.
Bacterial cellulose (BC) is a promising unique material for various biomedical and cosmetic applications due to its morphology, mechanical strength, high purity, high water uptake, non-toxicity, chemical controllability, and biocompatibility. Today, extensive investigation is into the manufacturing of BC-based composites with other components such as nanoparticles, synthetic polymers, natural polymers, carbon materials, and biomolecules, which will allow the development of a wide range of biomedical and cosmetic products. Moreover, the addition of different reinforcement substances into BC and the organized arrangement of BC nano-fibers have proven a promising improvement in their properties for biomedical applications. This review paper highlights the progress in synthesizing BC-based composites and their applications in biomedical fields, such as wound healing, drug delivery, tissue engineering, and cancer treatment. It emphasizes high-performance BC-based materials and cosmetic applications. Furthermore, it presents challenges yet to be defeated and future possibilities for BC-based composites for biomedical and cosmetic applications.
细菌纤维素 (BC) 因其形态、机械强度、高纯度、高吸水性、无毒、化学可控性和生物相容性而成为各种生物医学和化妆品应用的有前途的独特材料。如今,人们正在广泛研究制造基于 BC 的复合材料,这些复合材料中包含纳米粒子、合成聚合物、天然聚合物、碳材料和生物分子等其他成分,这将使各种生物医学和化妆品产品的开发成为可能。此外,将不同的增强物质添加到 BC 中并对 BC 纳米纤维进行有序排列,已被证明可以显著改善其用于生物医学应用的性能。本文综述了合成基于 BC 的复合材料的进展及其在生物医学领域的应用,如伤口愈合、药物输送、组织工程和癌症治疗。它强调了高性能基于 BC 的材料和化妆品应用。此外,它还介绍了基于 BC 的复合材料在生物医学和化妆品应用方面尚未克服的挑战和未来的可能性。