• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Interaction of the inflammatory response and megakaryocytes in COVID-19 infection.

作者信息

Battina Hanisha L, Alentado Vincent J, Srour Edward F, Moliterno Alison R, Kacena Melissa A

机构信息

Department of Orthopaedic Surgery, Indiana University School of Medicine, IN.

Department of Neurological Surgery, Indiana University School of Medicine, IN.

出版信息

Exp Hematol. 2021 Dec;104:32-39. doi: 10.1016/j.exphem.2021.09.005. Epub 2021 Sep 23.

DOI:10.1016/j.exphem.2021.09.005
PMID:34563606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8459550/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ea/8459550/1625437b2014/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ea/8459550/1625437b2014/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ea/8459550/1625437b2014/gr1_lrg.jpg

相似文献

1
Interaction of the inflammatory response and megakaryocytes in COVID-19 infection.新冠病毒感染中炎症反应与巨核细胞的相互作用
Exp Hematol. 2021 Dec;104:32-39. doi: 10.1016/j.exphem.2021.09.005. Epub 2021 Sep 23.
2
Platelets: "multiple choice" effectors in the immune response and their implication in COVID-19 thromboinflammatory process.血小板：免疫反应中的“多项选择”效应因子及其在 COVID-19 血栓炎症过程中的意义。
Int J Lab Hematol. 2021 Oct;43(5):895-906. doi: 10.1111/ijlh.13516. Epub 2021 Mar 22.
3
[Involvement of the complement cascade in severe forms of COVID-19].[补体级联反应在重症新型冠状病毒肺炎中的作用]
Med Sci (Paris). 2021 Apr;37(4):333-341. doi: 10.1051/medsci/2021021. Epub 2021 Apr 9.
4
Complement cascade in severe forms of COVID-19: Recent advances in therapy.补体级联反应在 COVID-19 严重形式中的作用：治疗的最新进展。
Eur J Immunol. 2021 Jul;51(7):1652-1659. doi: 10.1002/eji.202048959. Epub 2021 Apr 10.
5
The potential association between PARP14 and SARS-CoV-2 infection (COVID-19).PARP14 与严重急性呼吸综合征冠状病毒 2 感染（COVID-19）之间的潜在关联。
Future Med Chem. 2021 Mar;13(6):587-592. doi: 10.4155/fmc-2020-0226. Epub 2021 Jan 20.
6
What triggers severe COVID? Infected immune cells hold clues.是什么引发了重症新冠？受感染的免疫细胞提供了线索。
Nature. 2022 Apr;604(7905):231. doi: 10.1038/d41586-022-00965-z.
7
A proof of evidence supporting abnormal immunothrombosis in severe COVID-19: naked megakaryocyte nuclei increase in the bone marrow and lungs of critically ill patients.支持严重 COVID-19 中异常免疫血栓形成的证据：危重症患者骨髓和肺部中的裸巨核细胞核增加。
Platelets. 2020 Nov 16;31(8):1085-1089. doi: 10.1080/09537104.2020.1810224. Epub 2020 Aug 28.
8
Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy.COVID-19 中的细胞因子风暴：从病毒感染到免疫反应、诊断和治疗。
Int J Biol Sci. 2022 Jan 1;18(2):459-472. doi: 10.7150/ijbs.59272. eCollection 2022.
9
Can Natural Killer Cells Be a Principal Player in Anti-SARS-CoV-2 Immunity?自然杀伤细胞能否成为抗SARS-CoV-2免疫的主要参与者？
Front Immunol. 2020 Dec 7;11:586765. doi: 10.3389/fimmu.2020.586765. eCollection 2020.
10
A Review on Role of Inflammation in Coronavirus Disease.炎症在冠状病毒病中的作用综述
Endocr Metab Immune Disord Drug Targets. 2024;24(13):1488-1505. doi: 10.2174/0118715303265274231204075802.

引用本文的文献

1
Megakaryocyte phenotyping in response to SARS-CoV-2 variants.巨核细胞对新冠病毒变异株的表型分析
Platelets. 2025 Dec;36(1):2532459. doi: 10.1080/09537104.2025.2532459. Epub 2025 Jul 23.
2
The Role of TLR-2 in Lethal COVID-19 Disease Involving Medullary and Resident Lung Megakaryocyte Up-Regulation in the Microthrombosis Mechanism.TLR-2 在致命性 COVID-19 疾病中的作用：涉及微血栓形成机制中的骨髓和肺固有巨核细胞上调。
Cells. 2024 May 17;13(10):854. doi: 10.3390/cells13100854.
3
Clinical characteristics of pediatric inpatients infected with the SARS-CoV-2 Omicron variant-a retrospective observational cohort study.

本文引用的文献

1
Clinical applications of thrombopoietin silencing: A possible therapeutic role in COVID-19?血小板生成素沉默的临床应用：在 COVID-19 中可能具有治疗作用？
Cytokine. 2021 Oct;146:155634. doi: 10.1016/j.cyto.2021.155634. Epub 2021 Jul 3.
2
Characterization of Cellular Heterogeneity and an Immune Subpopulation of Human Megakaryocytes.人类巨核细胞的细胞异质性和免疫亚群特征。
Adv Sci (Weinh). 2021 Aug;8(15):e2100921. doi: 10.1002/advs.202100921. Epub 2021 May 26.
3
Assessing Brain Capillaries in Coronavirus Disease 2019.评估 2019 年冠状病毒病中的脑毛细血管。
感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）奥密克戎变异株的儿科住院患者的临床特征——一项回顾性观察队列研究
Transl Pediatr. 2023 Jul 31;12(7):1396-1402. doi: 10.21037/tp-23-292. Epub 2023 Jul 25.
4
Alterations in the megakaryocyte transcriptome impacts platelet function in sepsis and COVID-19 infection.巨核细胞转录组的改变影响脓毒症和 COVID-19 感染中的血小板功能。
Thromb Res. 2023 Nov;231:247-254. doi: 10.1016/j.thromres.2023.05.015. Epub 2023 May 19.
5
The impact of platelets on pulmonary microcirculation throughout COVID-19 and its persistent activating factors.血小板对 COVID-19 全病程及持续激活因素肺微循环的影响。
Front Immunol. 2022 Sep 28;13:955654. doi: 10.3389/fimmu.2022.955654. eCollection 2022.
6
Increased platelet activation and platelet-inflammasome engagement during chikungunya infection.在基孔肯雅热感染期间血小板活化和血小板炎症小体结合增加。
Front Immunol. 2022 Sep 15;13:958820. doi: 10.3389/fimmu.2022.958820. eCollection 2022.
7
SARS-CoV-2 and Endothelial Cells: Vascular Changes, Intussusceptive Microvascular Growth and Novel Therapeutic Windows.严重急性呼吸综合征冠状病毒2与内皮细胞：血管变化、套叠式微血管生长及新的治疗窗口
Biomedicines. 2022 Sep 9;10(9):2242. doi: 10.3390/biomedicines10092242.
8
Relationship Between Platelet Count and In-hospital Mortality in Adult Patients With COVID-19: A Retrospective Cohort Study.成人 COVID-19 患者血小板计数与院内死亡率的关系：一项回顾性队列研究
Front Med (Lausanne). 2022 Jun 14;9:802412. doi: 10.3389/fmed.2022.802412. eCollection 2022.
9
The Impacts of COVID-19 on Musculoskeletal Health.新型冠状病毒肺炎对肌肉骨骼健康的影响。
Curr Osteoporos Rep. 2022 Aug;20(4):213-225. doi: 10.1007/s11914-022-00734-x. Epub 2022 Jun 20.
10
Platelet Megakaryocyte: Who Is the Real Bandleader of Thromboinflammation in Sepsis?血小板 巨核细胞：在脓毒症中，谁才是血栓炎症真正的领衔主演？
Cells. 2022 Apr 30;11(9):1507. doi: 10.3390/cells11091507.
JAMA Neurol. 2021 Jun 1;78(6):760-762. doi: 10.1001/jamaneurol.2021.0225.
4
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine.自身免疫性抗体针对 I 型干扰素可能导致黄热病减毒活疫苗的不良反应。
J Exp Med. 2021 Apr 5;218(4). doi: 10.1084/jem.20202486.
5
Epidemiological characteristics of COVID-19 cases and estimates of the reproductive numbers 1 month into the epidemic, Italy, 28 January to 31 March 2020.2020 年 1 月 28 日至 3 月 31 日意大利新冠疫情流行 1 个月时的病例流行病学特征及繁殖数估计
Euro Surveill. 2020 Dec;25(49). doi: 10.2807/1560-7917.ES.2020.25.49.2000790.
6
Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis.托珠单抗治疗 COVID-19 患者的疗效和安全性：一项实时系统评价和荟萃分析。
Clin Microbiol Infect. 2021 Feb;27(2):215-227. doi: 10.1016/j.cmi.2020.10.036. Epub 2020 Nov 5.
7
Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein.人造血干/祖细胞和免疫细胞体外响应 SARS-CoV-2 刺突蛋白。
Stem Cell Rev Rep. 2021 Feb;17(1):253-265. doi: 10.1007/s12015-020-10056-z. Epub 2020 Oct 21.
8
Lung megakaryocytes are immune modulatory cells.肺巨核细胞是免疫调节细胞。
J Clin Invest. 2021 Jan 4;131(1). doi: 10.1172/JCI137377.
9
Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia.血小板促进新冠病毒肺炎中的血栓炎症反应。
Arterioscler Thromb Vasc Biol. 2020 Dec;40(12):2975-2989. doi: 10.1161/ATVBAHA.120.315175. Epub 2020 Oct 14.
10
The Impact of COVID-19 Disease on Platelets and Coagulation.新型冠状病毒疾病对血小板和凝血的影响。
Pathobiology. 2021;88(1):15-27. doi: 10.1159/000512007. Epub 2020 Oct 13.