Schiller Martin, Solger Kim, Leipold Stefanie, Kerl Hans Ulrich, Kick Wolfgang
Internal Medicine, HochFranken Hospitals, Munchberg, Germany.
Department of Radiology, HochFranken Hospitals, Munchberg, Germany.
J Community Hosp Intern Med Perspect. 2021 Sep 20;11(5):590-596. doi: 10.1080/20009666.2021.1957555. eCollection 2021.
Coronavirus disease 2019 has rapidly spread around the globe and various comorbidities, such as diabetes have been recognized as risk factors for an unfavorable outcome. We analyzed a cohort of COVID-19 patients (n = 75) treated at a German community hospital. With a focus on diabetes mellitus, we evaluated the impact of distinct comorbidities on the COVID-19 disease course. The duration of hospital stay was prolonged if diabetes was present. An older age was associated with a poor outcome. The percentage of non-survivors increased in the presence of congestive heart failure or chronic kidney disease. In the group of diabetes patients, mortality was increased if any organ complication was present and diabetic nephropathy or the combination of obesity plus diabetes were by far the most important risk factors. Taken together, an older age, congestive heart failure, and chronic kidney disease significantly influenced COVID-19 disease course and survival. Diabetic nephropathy or the combination of obesity plus diabetes had the strongest impact on patients' outcome.
2019冠状病毒病已在全球迅速传播，糖尿病等各种合并症已被确认为不良预后的危险因素。我们分析了一家德国社区医院收治的一组COVID-19患者（n = 75）。以糖尿病为重点，我们评估了不同合并症对COVID-19病程的影响。如果存在糖尿病，住院时间会延长。年龄较大与预后不良相关。存在充血性心力衰竭或慢性肾脏病时，非幸存者的比例会增加。在糖尿病患者组中，如果出现任何器官并发症，死亡率会增加，而糖尿病肾病或肥胖加糖尿病的组合是迄今为止最重要的危险因素。总体而言，年龄较大、充血性心力衰竭和慢性肾脏病显著影响COVID-19的病程和生存。糖尿病肾病或肥胖加糖尿病的组合对患者预后的影响最大。
