基于 EEG 的镜像神经元活动证据来自应用介导的中风患者观察。
EEG-Based Evidence of Mirror Neuron Activity from App-Mediated Stroke Patient Observation.
机构信息
Department of Physical Therapy, City Hospital, Seomun-daero 654, Gwangju 61710, Korea.
Department of Physical Therapy, College of Health Science, Honam University, Honamdae-gil 100, Gwangju 62399, Korea.
出版信息
Medicina (Kaunas). 2021 Sep 17;57(9):979. doi: 10.3390/medicina57090979.
: The mirror neuron system in the sensorimotor region of the cerebral cortex is equally activated during both action observation and execution. Action observation training mimics the functioning of the mirror neuron system, requiring patients to watch and imitate the actions necessary to perform activities of daily living. StrokeCare is a user-friendly application based on the principles of action observation training, designed to assist people recovering from stroke. Therefore, when observing the daily life behavior provided in the StrokeCare app, whether the MNS is activated and mu inhibition appears. : We performed electroencephalography (EEG) on 24 patients with chronic stroke (infarction: 11, hemorrhage: 13) during tasks closely related to daily activities, such as dressing, undressing, and walking. The StrokeCare app provided action videos for patients to watch. Landscape imagery observation facilitated comparison among tasks. We analyzed the mu rhythm from the C3, CZ, and C4 regions and calculated the mean log ratios for comparison of mu suppression values. The EEG mu power log ratios were significantly suppressed during action observation in dressing, undressing, walking, and landscape conditions, in decreasing order. However, there were no significant activity differences in the C3, C4 and CZ regions. The dressing task showed maximum suppression after a color spectrum was used to map the relative power values of the mu rhythm for each task. These findings reveal that the human mirror neuron system was more strongly activated during observation of actions closely related to daily life activities than landscape images.
大脑感觉运动区域的镜像神经元系统在进行动作观察和执行时会被同等激活。动作观察训练模拟了镜像神经元系统的功能，要求患者观看并模仿完成日常生活活动所需的动作。StrokeCare 是一款基于动作观察训练原理设计的用户友好型应用程序，旨在帮助中风患者康复。因此，当观察 StrokeCare 应用程序中提供的日常生活行为时，是否激活了 MNS 并出现 mu 抑制。
我们对 24 名慢性中风患者（梗死：11 例，出血：13 例）进行了脑电图（EEG）检测，这些患者在与日常活动密切相关的任务中，如穿衣、脱衣和行走时进行任务。StrokeCare 应用程序为患者提供了观看动作的视频。景观图像观察有助于任务之间的比较。我们分析了 C3、CZ 和 C4 区域的 mu 节律，并计算了 mu 抑制值的平均对数比进行比较。在穿衣、脱衣、行走和景观条件下进行动作观察时，EEG mu 功率对数比明显受到抑制，抑制程度依次降低。然而，在 C3、C4 和 CZ 区域没有明显的活动差异。在使用颜色频谱为每个任务的 mu 节律相对功率值进行映射后，穿衣任务显示出最大的抑制。
这些发现表明，在观察与日常生活活动密切相关的动作时，人类镜像神经元系统比观察景观图像时被更强地激活。
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