Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos (URJC), Madrid, Spain
Department of Internal Medicine, Hospital Universitario Fundación Alcorcón, Madrid, Spain.
Diabetes. 2021 Dec;70(12):2917-2921. doi: 10.2337/db21-0329. Epub 2021 Sep 27.
This study investigated the association of diabetes in patients who recovered from severe acute respiratory syndrome coronavirus 2 infection with the presence of long-term post-coronavirus disease (COVID) symptoms. A case-control study that included individuals hospitalized during the first wave of the pandemic was conducted. Patients with a previous diagnosis of diabetes and under medical control were considered case subjects. Two age- and sex-matched patients without presenting diabetes per case subject were recruited as control subjects. Hospitalization and clinical data were collected from hospital medical records. Patients were scheduled for a telephone interview. A list of post-COVID symptoms was systematically evaluated, but participants were invited to freely report any symptom. The Hospital Anxiety and Depression Scale and the Pittsburgh Sleep Quality Index were used to assess anxiety and depressive symptoms, and sleep quality, respectively. Multivariable conditional logistic regression models were constructed. Overall, 145 patients with diabetes and 144 control subjects without diabetes who had recovered from COVID-19 were assessed at 7.2 (SD 0.6) months after hospital discharge. The number of post-COVID symptoms was similar between groups (incident rate ratio 1.06, 95% CI 0.92-1.24, = 0.372). The most prevalent post-COVID symptoms were fatigue, dyspnea on exertion, and pain. No between-groups differences in any post-COVID symptom were observed. Similarly, no differences in limitations with daily living activities were found between patients with and without diabetes. Diabetes was not a risk factor for experiencing long-term post-COVID symptoms.
这项研究调查了在从严重急性呼吸综合征冠状病毒 2 感染中康复的患者中，糖尿病与长期新冠病毒疾病（COVID）后症状存在的关联。进行了一项包括大流行第一波期间住院的个体的病例对照研究。患有糖尿病既往诊断并接受医疗控制的患者被视为病例组。每例病例组招募两名年龄和性别匹配、无糖尿病的患者作为对照组。从医院病历中收集住院和临床数据。患者安排进行电话访谈。系统评估了一系列新冠后症状，但邀请患者自由报告任何症状。使用医院焦虑和抑郁量表和匹兹堡睡眠质量指数分别评估焦虑和抑郁症状以及睡眠质量。构建了多变量条件逻辑回归模型。总体而言，在 COVID-19 康复后 7.2 个月（SD 0.6），评估了 145 名患有糖尿病的患者和 144 名无糖尿病的对照组患者。两组的新冠后症状数量相似（发病率比 1.06，95%CI 0.92-1.24， = 0.372）。最常见的新冠后症状是疲劳、用力时呼吸困难和疼痛。两组之间没有观察到任何新冠后症状的差异。同样，患有和不患有糖尿病的患者在日常生活活动受限方面也没有差异。糖尿病不是经历长期新冠后症状的危险因素。
