Khalid Khizer, Padda Jaskamal, Komissarov Anton, Colaco Lanson B, Padda Sandeep, Khan Armughan S, Campos Victor Melt, Jean-Charles Gutteridge
Internal Medicine, Jean-Charles (JC) Medical Center, Orlando, USA.
Internal Medicine, Avalon University School of Medicine, Willemstad, CUW.
Cureus. 2021 Aug 23;13(8):e17387. doi: 10.7759/cureus.17387. eCollection 2021 Aug.
Chronic obstructive pulmonary disease (COPD) is a chronic illness that is widely prevalent within the United States and has been frequently associated with heart failure (HF). COPD is associated with progressive damage and inflammation of the airways leading to airflow obstruction and inadequate gas exchange. HF represents a decline in the normal functioning of the heart resulting in insufficient pumping of blood through the circulatory system. COPD and HF present with similar signs and symptoms with some variation. There are many specific diagnostic tests and treatment modalities which we use to diagnose COPD and HF, but it becomes an issue when you come across a patient who has both conditions simultaneously. For example, attempting to use an X-ray to diagnose HF in a COPD patient is next to impossible because the results are manipulated by the COPD disease process. This is the case with many other diagnostic tests such as an electrocardiogram (ECG), chest radiography (X-ray), B-type natriuretic peptide (BNP), echocardiogram, cardiac magnetic resonance imaging (CMR), pulmonary function test (PFT), arterial blood gas (ABG), and exercise stress testing. When a patient has both COPD and HF, it becomes more difficult to treat. Many treatments for HF have negative impacts on COPD patients and vice-versa, whereas some have also shown positive clinical outcomes in both diseases. It is agreeable that treatment has to be patient-centered and it can vary from case to case depending on the severity of the disease. Ultimately, in this review, we discuss COPD and HF and how they interplay in their diagnostic and treatment modalities to gain a better understanding of how to effectively manage patients who have been diagnosed with both conditions.
慢性阻塞性肺疾病(COPD)是一种在美国广泛流行的慢性疾病,常与心力衰竭(HF)相关。COPD与气道的渐进性损伤和炎症有关,导致气流阻塞和气体交换不足。HF表示心脏正常功能下降,导致通过循环系统的血液泵出不足。COPD和HF表现出相似的体征和症状,但存在一些差异。我们使用许多特定的诊断测试和治疗方法来诊断COPD和HF,但当遇到同时患有这两种疾病的患者时,就会出现问题。例如,试图在COPD患者中使用X射线诊断HF几乎是不可能的,因为结果会受到COPD疾病过程的影响。许多其他诊断测试也是如此,如心电图(ECG)、胸部X线摄影(X射线)、B型利钠肽(BNP)、超声心动图、心脏磁共振成像(CMR)、肺功能测试(PFT)、动脉血气(ABG)和运动压力测试。当患者同时患有COPD和HF时,治疗会变得更加困难。许多HF治疗方法对COPD患者有负面影响,反之亦然,而有些治疗方法在这两种疾病中也显示出积极的临床结果。一致认为治疗必须以患者为中心,并且根据疾病的严重程度,治疗方法可能因病例而异。最终,在本综述中,我们讨论COPD和HF以及它们在诊断和治疗方式中的相互作用,以更好地理解如何有效管理同时被诊断患有这两种疾病的患者。