Klimov N E, Grigor'eva V M
Antibiotiki. 1978 Mar;23(3):219-22.
The experiments showed that the method of direct plating of tetracycline tablet suspensions on solid nutrient media containing magnesium sulfate may be used for determination of microbial contamination. The method provided determination of both the antibiotic resistant and the antibiotic sensitive organisms which may be present in the drug. Dilution of the basic suspensions increased the probability of the microbe detection in the tablets.
实验表明，将四环素片悬浮液直接接种在含有硫酸镁的固体营养培养基上的方法可用于测定微生物污染情况。该方法能测定药物中可能存在的抗抗生素和对抗生素敏感的微生物。对基础悬浮液进行稀释增加了在片剂中检测到微生物的可能性。
