Division of Infectious Disease, Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin-si, Gyeonggi-do, Republic of Korea.
Data Science Team (Biostatistician), Center for Digital Health, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin-si, Gyeonggi-do, Republic of Korea.
PLoS One. 2021 Oct 1;16(10):e0258236. doi: 10.1371/journal.pone.0258236. eCollection 2021.
All healthcare workers (HCWs) in Yongin Severance Hospital were allocated to receive the ChAdOx1 nCov-19 vaccine according to national policy. A report of thrombosis and thrombocytopenia syndrome (TTS) associated with ChAdOx1 nCoV-19 led to hesitancy about receiving the second dose among HCWs who had received the first dose.
From 7 to 14 May, 2021, we performed a survey to identify the factors associated with hesitancy about receiving the second vaccine dose among HCWs at the hospital who had received the first dose of the vaccine. Based on survey results, a hospital-wide campaign was implemented on 18 May 2021 to improve vaccine coverage. HCWs who completed the second dose completed a self-administered questionnaire to evaluate the effect of the campaign.
Of 1,171 HCWs who had received the first dose of the vaccine, 71.5% completed the online survey, of whom 3.7% refused to take the second dose and 22.3% showed hesitancy. Hesitancy to receive a second dose was significantly associated with age under 30 years and concerns about TTS, and was less common among those who trusted effectiveness and safety of the vaccine. Among HCWs who received the first dose, 96.2% completed vaccination with the second dose between 27 May and 4 June, 2021. Of those who answered the questionnaire asked about the timing of their decision to receive the second dose, 57.1% reported that they were motivated by the hospital-wide campaign.
A tailored intervention strategy based on a survey can improve COVID-19 vaccination uptake among HCWs.
根据国家政策，龙仁Severance 医院的所有医护人员（HCWs）都被分配接种 ChAdOx1 nCov-19 疫苗。与 ChAdOx1 nCoV-19 相关的血栓和血小板减少症综合征（TTS）报告导致已接种第一剂疫苗的 HCWs 对接种第二剂疫苗犹豫不决。
2021 年 5 月 7 日至 14 日，我们进行了一项调查，以确定在已接种第一剂疫苗的医院 HCWs 中，对接种第二剂疫苗犹豫不决的相关因素。根据调查结果，2021 年 5 月 18 日在全院范围内开展了一项活动，以提高疫苗接种率。完成第二剂疫苗接种的 HCWs 完成了一份自我管理的问卷，以评估该活动的效果。
在 1171 名已接种第一剂疫苗的 HCWs 中，有 71.5%完成了在线调查，其中 3.7%拒绝接种第二剂，22.3%表现出犹豫。对接种第二剂疫苗的犹豫与年龄在 30 岁以下和对 TTS 的担忧显著相关，而对疫苗的有效性和安全性信任的人则较少。在已接种第一剂疫苗的 HCWs 中，96.2%在 2021 年 5 月 27 日至 6 月 4 日之间完成了第二剂疫苗接种。在回答关于他们决定接种第二剂疫苗时间的问卷调查的人当中，57.1%报告说他们受到了全院范围活动的激励。
基于调查的量身定制的干预策略可以提高 HCWs 的 COVID-19 疫苗接种率。
