使用未经批准的基因符号的风险。
The risks of using unapproved gene symbols.
机构信息
HUGO Gene Nomenclature Committee, European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
HUGO Gene Nomenclature Committee, European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK; Department of Haematology, University of Cambridge School of Clinical Medicine, Cambridge CB2 0PT, UK.
出版信息
Am J Hum Genet. 2021 Oct 7;108(10):1813-1816. doi: 10.1016/j.ajhg.2021.09.004.
The use of approved nomenclature in publications is vital to enable effective scientific communication and is particularly crucial when discussing genes of clinical relevance. Here, we discuss several examples of cases where the failure of researchers to use a HUGO Gene Nomenclature Committee (HGNC)-approved symbol in publications has led to confusion between unrelated human genes in the literature. We also inform authors of the steps they can take to ensure that they use approved nomenclature in their manuscripts and discuss how referencing HGNC IDs can remove ambiguity when referring to genes that have previously been published with confusing alias symbols.
在出版物中使用经过批准的命名法对于实现有效的科学交流至关重要，特别是在讨论具有临床相关性的基因时更是如此。在这里，我们讨论了一些研究人员在出版物中未能使用人类基因命名委员会（HGNC）批准的符号的情况，这些情况导致文献中不相关的人类基因之间产生混淆。我们还向作者介绍了他们可以采取的确保在稿件中使用经批准的命名法的步骤，并讨论了在引用以前使用混淆别名符号发表的基因时，引用 HGNC ID 如何消除歧义。
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