Department of Environmental and Natural Resources Management, University of Patras, Greece.
Department of Occupational and Industrial Hygiene, National School of Public Health, Greece.
Ind Health. 2022 Feb 8;60(1):47-61. doi: 10.2486/indhealth.2021-0024. Epub 2021 Oct 8.
Shipyards are industrial areas where workers are likely exposed to environmental pollutants such as welding fumes, fine organic solvent and dye dust, that render the occupational environment a high risk one. Assessing the risk that workers are exposed to is a high critical factor in improving their working conditions. The present study aims to investigate the potential genetic damage to workers exposed to a harsh environment in a Greek shipyard. It is focused on assessing the percentage of induced micronuclei, as well as on changes in the various cell types of shipyard workers' oral mucosa epithelium by implementing the buccal micronucleus cytome assay. Exposed workers appeared with statistically significant induced micronuclei as compared to office employees. Statistically, significant cell lesions were detected and are related to workers' exposure to environmental conditions. The workers' smoking habit contributed as well to the observed buccal epithelial cell alterations. The observed data signify the high-risk workers are exposed; resulting in the shipyard's management the need to implement measures improving the working environment conditions and to reevaluate the workers' personal protective equipment requirements.
造船厂是工人可能接触到环境污染物的工业区域,如焊接烟尘、有机溶剂和染料粉尘,这使得职业环境成为高风险环境。评估工人所面临的风险是改善工作条件的关键因素。本研究旨在调查在希腊造船厂恶劣环境中工作的工人所面临的潜在遗传损伤。它集中评估诱导微核的百分比,以及通过实施口腔黏膜细胞微核细胞分析来评估造船厂工人口腔黏膜上皮的各种细胞类型的变化。与办公室员工相比,暴露于环境中的工人出现了具有统计学意义的诱导微核。统计学上,检测到与工人接触环境条件有关的细胞病变。工人的吸烟习惯也导致了观察到的口腔上皮细胞变化。观察到的数据表明高风险工人面临暴露,这促使船厂管理层有必要采取措施改善工作环境条件,并重新评估工人个人防护设备的要求。