用痘苗病毒-狂犬病糖蛋白重组病毒疫苗对浣熊进行口服免疫和保护。
Oral immunization and protection of raccoons (Procyon lotor) with a vaccinia-rabies glycoprotein recombinant virus vaccine.
作者信息
Rupprecht C E, Wiktor T J, Johnston D H, Hamir A N, Dietzschold B, Wunner W H, Glickman L T, Koprowski H
出版信息
Proc Natl Acad Sci U S A. 1986 Oct;83(20):7947-50. doi: 10.1073/pnas.83.20.7947.
Abstract
Animal rabies control has been frustrated by the existence of multiple wildlife reservoirs and the lack of efficacious oral vaccines. In this investigation, raccoons fed a vaccinia-rabies glycoprotein recombinant virus in a sponge bait developed rabies virus-neutralizing antibody (0.6-54.0 units) and resisted street rabies virus infection 28 and 205 days after feeding. Additional raccoons immunized by oral infusion with attenuated antigenic variants of rabies virus strains CVS-11 and ERA failed to develop rabies virus-neutralizing antibody. This work demonstrates the feasibility of a recombinant virus vaccine containing the rabies glycoprotein gene for immunization of raccoons, and possibly other wildlife, to obtain long-term protection against rabies.
摘要
多种野生动物宿主的存在以及缺乏有效的口服疫苗，使得动物狂犬病的防控工作受阻。在本研究中，浣熊食用了含有痘苗狂犬病糖蛋白重组病毒的海绵诱饵后，产生了狂犬病病毒中和抗体（0.6 - 54.0 单位），并在喂食后28天和205天抵抗了街狂犬病毒感染。另外，通过口服灌注狂犬病病毒株CVS - 11和ERA的减毒抗原变异体免疫的浣熊未能产生狂犬病病毒中和抗体。这项工作证明了含有狂犬病糖蛋白基因的重组病毒疫苗用于浣熊以及可能的其他野生动物免疫以获得长期狂犬病防护的可行性。
相似文献
1
Oral immunization and protection of raccoons (Procyon lotor) with a vaccinia-rabies glycoprotein recombinant virus vaccine.用痘苗病毒-狂犬病糖蛋白重组病毒疫苗对浣熊进行口服免疫和保护。
Proc Natl Acad Sci U S A. 1986 Oct;83(20):7947-50. doi: 10.1073/pnas.83.20.7947.
2
Efficacy of a vaccinia-rabies glycoprotein recombinant virus vaccine in raccoons (Procyon lotor).痘苗病毒-狂犬病糖蛋白重组病毒疫苗对浣熊（北美浣熊）的效力
Rev Infect Dis. 1988 Nov-Dec;10 Suppl 4:S803-9. doi: 10.1093/clinids/10.supplement_4.s803.
3
Safety and immunogenicity of Ontario Rabies Vaccine Bait (ONRAB) in the first us field trial in raccoons (Procyon lotor).安大略省狂犬病疫苗诱饵（ONRAB）在美国首次浣熊（北美浣熊）野外试验中的安全性和免疫原性。
J Wildl Dis. 2014 Jul;50(3):582-95. doi: 10.7589/2013-08-207. Epub 2014 May 7.
4
Potential effect of prior raccoonpox virus infection in raccoons on vaccinia-based rabies immunization.浣熊先前感染浣熊痘病毒对基于痘苗的狂犬病免疫接种的潜在影响。
BMC Immunol. 2008 Oct 3;9:57. doi: 10.1186/1471-2172-9-57.
5
Immune response and protection in raccoons (Procyon lotor) following consumption of baits containing ONRAB®, a human adenovirus rabies glycoprotein recombinant vaccine.浣熊（北美浣熊）食用含人腺病毒狂犬病糖蛋白重组疫苗ONRAB®的诱饵后的免疫反应及保护作用
J Wildl Dis. 2012 Oct;48(4):1010-20. doi: 10.7589/2012-01-023.
6
Cerebrospinal fluid analysis of rabid and vaccinia-rabies glycoprotein recombinant, orally vaccinated raccoons (Procyon lotor).
Am J Vet Res. 1989 Mar;50(3):364-7.
7
Oral vaccination of racoons (Procyon lotor) with baculovirus-expressed rabies virus glycoprotein.用杆状病毒表达的狂犬病病毒糖蛋白对浣熊（北美浣熊）进行口服疫苗接种。
Vaccine. 1993;11(9):925-8. doi: 10.1016/0264-410x(93)90379-c.
8
Oral efficacy of an attenuated rabies virus vaccine in skunks and raccoons.减毒狂犬病病毒疫苗对臭鼬和浣熊的口服效果。
J Wildl Dis. 2002 Apr;38(2):420-7. doi: 10.7589/0090-3558-38.2.420.
9
Comparing ONRAB® AND RABORAL V-RG® oral rabies vaccine field performance in raccoons and striped skunks, New Brunswick, Canada, and Maine, USA.比较ONRAB®和RABORAL V-RG®口服狂犬病疫苗在加拿大新不伦瑞克省和美国缅因州浣熊和条纹臭鼬中的野外性能。
J Wildl Dis. 2012 Jan;48(1):157-67. doi: 10.7589/0090-3558-48.1.157.
10
Oral vaccination of raccoons (Procyon lotor) with an attenuated (SAD-B19) rabies virus vaccine.用减毒（SAD-B19）狂犬病病毒疫苗对浣熊（北美浣熊）进行口服接种。
J Wildl Dis. 1989 Oct;25(4):548-54. doi: 10.7589/0090-3558-25.4.548.
引用本文的文献
1
Trimerized S expressed by modified vaccinia virus Ankara (MVA) confers superior protection against lethal SARS-CoV-2 challenge in mice.三聚物化 S 由改良安卡拉痘苗病毒（MVA）表达，可显著提高小鼠对致死性 SARS-CoV-2 攻击的保护作用。
J Virol. 2024 Jul 23;98(7):e0052124. doi: 10.1128/jvi.00521-24. Epub 2024 Jun 14.
2
Detection of Apparent Early Rabies Infection by LN34 Pan-Lyssavirus Real-Time RT-PCR Assay in Pennsylvania.宾夕法尼亚州通过 LN34 泛狂犬病病毒实时 RT-PCR 检测法检测明显的早期狂犬病感染。
Viruses. 2022 Aug 23;14(9):1845. doi: 10.3390/v14091845.
3
Review of Oral Rabies Vaccination of Dogs and Its Application in India.犬用口服狂犬病疫苗的综述及其在印度的应用。
Viruses. 2022 Jan 14;14(1):155. doi: 10.3390/v14010155.
4
Impact of Molecular Modifications on the Immunogenicity and Efficacy of Recombinant Raccoon Poxvirus-Vectored Rabies Vaccine Candidates in Mice.分子修饰对重组浣熊痘病毒载体狂犬病候选疫苗在小鼠体内免疫原性和效力的影响
Vaccines (Basel). 2021 Dec 4;9(12):1436. doi: 10.3390/vaccines9121436.
5
Why do poxviruses still matter?痘病毒为何仍然重要？
Cell Biosci. 2021 May 22;11(1):96. doi: 10.1186/s13578-021-00610-8.
6
Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines.兽医学中的新型疫苗技术：人类医学疫苗的先驱
Front Vet Sci. 2021 Apr 15;8:654289. doi: 10.3389/fvets.2021.654289. eCollection 2021.
7
Responsiveness of various reservoir species to oral rabies vaccination correlates with differences in vaccine uptake of mucosa associated lymphoid tissues.各种储层物种对口服狂犬病疫苗的反应性与黏膜相关淋巴组织对疫苗的摄取率差异相关。
Sci Rep. 2020 Feb 19;10(1):2919. doi: 10.1038/s41598-020-59719-4.
8
Rabies Virus Antibodies from Oral Vaccination as a Correlate of Protection against Lethal Infection in Wildlife.口服疫苗产生的狂犬病病毒抗体作为野生动物抵抗致命感染的保护相关性
Trop Med Infect Dis. 2017 Jul 21;2(3):31. doi: 10.3390/tropicalmed2030031.
9
Raccoon () biomarker and rabies antibody response to varying oral rabies vaccine bait densities in northwestern Pennsylvania.宾夕法尼亚州西北部浣熊对不同口服狂犬病疫苗诱饵密度的生物标志物及狂犬病抗体反应
Heliyon. 2018 Sep 6;4(9):e00754. doi: 10.1016/j.heliyon.2018.e00754. eCollection 2018 Sep.
10
Hazard Characterization of Modified Vaccinia Virus Ankara Vector: What Are the Knowledge Gaps?安卡拉痘苗病毒载体的危害特征：有哪些知识空白？
Viruses. 2017 Oct 29;9(11):318. doi: 10.3390/v9110318.
本文引用的文献
1
An Attenuated Rabies Vaccine for Domestic Animals Produced in Tissue Culture.一种在组织培养中生产的用于家畜的减毒狂犬病疫苗。
Can Vet J. 1964 Nov;5(11):279-86.
2
Growth of rabies virus in non-nervous tissue culture.狂犬病病毒在非神经组织培养中的生长
Proc Soc Exp Biol Med. 1958 Jun;98(2):223-5. doi: 10.3181/00379727-98-23997.
3
Dual role of the immune response in street rabiesvirus infection of mice.免疫反应在小鼠街狂犬病毒感染中的双重作用。
Infect Immun. 1982 Jan;35(1):213-21. doi: 10.1128/iai.35.1.213-221.1982.
4
The epidemiology of fox rabies in Europe.欧洲狐狸狂犬病的流行病学
Epidemiol Rev. 1980;2:71-96. doi: 10.1093/oxfordjournals.epirev.a036227.
5
Anti-idiotypic antibodies induce neutralizing antibodies to rabies virus glycoprotein.抗独特型抗体可诱导产生针对狂犬病病毒糖蛋白的中和抗体。
J Virol. 1983 Dec;48(3):660-6. doi: 10.1128/JVI.48.3.660-666.1983.
6
Expression of rabies virus glycoprotein from a recombinant vaccinia virus.重组痘苗病毒中狂犬病病毒糖蛋白的表达
Nature. 1984;312(5990):163-6. doi: 10.1038/312163a0.
7
Characterization of an antigenic determinant of the glycoprotein that correlates with pathogenicity of rabies virus.一种与狂犬病病毒致病性相关的糖蛋白抗原决定簇的特性分析。
Proc Natl Acad Sci U S A. 1983 Jan;80(1):70-4. doi: 10.1073/pnas.80.1.70.
8
Antigenic variants of rabies virus.狂犬病病毒的抗原变异体。
J Exp Med. 1980 Jul 1;152(1):99-112. doi: 10.1084/jem.152.1.99.
9
Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene.含有狂犬病病毒糖蛋白基因的痘苗病毒重组体对狂犬病的防护作用。
Proc Natl Acad Sci U S A. 1984 Nov;81(22):7194-8. doi: 10.1073/pnas.81.22.7194.
10
Oral vaccination of foxes against rabies.
Am J Epidemiol. 1971 Jun;93(6):487-90. doi: 10.1093/oxfordjournals.aje.a121283.
Zotero 插件