有饮食障碍史个体的生活应激事件：病例对照比较。
Stressful life events among individuals with a history of eating disorders: a case-control comparison.
机构信息
Regional Department for Eating Disorders, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
出版信息
BMC Psychiatry. 2021 Oct 13;21(1):501. doi: 10.1186/s12888-021-03499-2.
BACKGROUND
Experiencing stressful life events (SLEs) can negatively impact mental health and increase risk for psychiatric disorders including eating disorders (EDs). Previous research has shown that childhood sexual abuse is associated with some EDs, but less is known about the association between other non-sexual SLEs and EDs.
METHOD
A case-control study of individuals with (n = 495, age mean ± SD = 29.1 ± 9.8 years) and without (n = 395, age = 30.2 ± 11.7) self-reported lifetime history of EDs was conducted to compare history of self-reported SLEs. Participants reported history of sexual (e.g., rape, other sexual assault) and non-sexual (e.g., emotional abuse, assault, bereavement) life events using an adaptation of the Stressful Life Events Screening Questionnaire. Individuals with EDs were divided into ED subtypes along the restricting - binge eating/purging spectrum to examine subtype differences. Logistic regressions were conducted for each SLE and ED subtype to obtain odds ratios (ORs). We report p-values corrected for multiple comparisons.
RESULTS
Exposure to any SLE was significantly more common in individuals with EDs than in controls (OR = 2.47, p < .001). Specifically, rape, other sexual assault, and emotional abuse were significantly more common among individuals with a history of binge-eating/purging ED subtypes (ORs = 2.15-3.58, p's < .01) compared with controls. Furthermore, history of life-threatening disease and loss of a close relative/partner/friend were associated with some ED subtypes. The association between SLEs and EDs was stronger for individuals who had experienced multiple SLEs.
CONCLUSION
By investigating a range of different SLEs, we showed that both sexual and non-sexual SLEs were more common in individuals with a history of EDs (binge-eating/purging subtypes) than controls. Results highlight the importance of assessing a variety of past SLEs in risk assessment for different EDs.
背景
经历压力性生活事件（SLE）会对心理健康产生负面影响，并增加患精神疾病的风险，包括饮食障碍（ED）。先前的研究表明，儿童期性虐待与某些 ED 有关，但对于其他非性 SLE 与 ED 之间的关联知之甚少。
方法
对有（n=495，年龄均值±标准差=29.1±9.8 岁）和无（n=395，年龄=30.2±11.7 岁）自我报告终生 ED 病史的个体进行病例对照研究，以比较自我报告的 SLE 病史。参与者使用压力性生活事件筛查问卷的改编版报告性（例如，强奸，其他性侵犯）和非性（例如，情感虐待，攻击，丧亲）生活事件的历史。将 ED 患者分为限制型-暴食/清除型谱内的 ED 亚型，以检查亚型差异。对每种 SLE 和 ED 亚型进行逻辑回归以获得优势比（OR）。我们报告了经多次比较校正的 p 值。
结果
暴露于任何 SLE 在 ED 患者中比在对照组中更为常见（OR=2.47，p<0.001）。具体而言，与对照组相比，有暴食/清除 ED 亚型病史的个体中，强奸、其他性侵犯和情感虐待更为常见（ORs=2.15-3.58，p<.01）。此外，威胁生命的疾病史和失去近亲/伴侣/朋友与某些 ED 亚型有关。经历多次 SLE 的个体 SLE 与 ED 之间的关联更强。
结论
通过调查一系列不同的 SLE，我们表明，经历过 ED（暴食/清除亚型）的个体中，性和非性 SLE 比对照组更为常见。结果强调了在不同 ED 的风险评估中评估各种过去 SLE 的重要性。
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