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新冠 superspreading 场所及相关建成环境和社会人口特征:基于空间网络框架和个体活动数据的研究。

The superspreading places of COVID-19 and the associated built-environment and socio-demographic features: A study using a spatial network framework and individual-level activity data.

机构信息

Institute of Space and Earth Information Science, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

Department of Geography and Resource Management and Institute of Space and Earth Information Science, The Chinese University of Hong Kong, Shatin, Hong Kong, China; Department of Human Geography and Spatial Planning, Utrecht University, 3584 CB, Utrecht, the Netherlands.

出版信息

Health Place. 2021 Nov;72:102694. doi: 10.1016/j.healthplace.2021.102694. Epub 2021 Oct 9.

Abstract

Previous studies observed that most COVID-19 infections were transmitted by a few individuals at a few high-risk places (e.g., bars or social gathering venues). These individuals, often called superspreaders, transmit the virus to an unexpectedly large number of people. Further, a small number of superspreading places (SSPs) where this occurred account for a large number of COVID-19 transmissions. In this study, we propose a spatial network framework for identifying the SSPs that disproportionately spread COVID-19. Using individual-level activity data of the confirmed cases in Hong Kong, we first identify the high-risk places in the first four COVID-19 waves using the space-time kernel density method (STKDE). Then, we identify the SSPs among these high-risk places by constructing spatial networks that integrate the flow intensity of the confirmed cases. We also examine what built-environment and socio-demographic features would make a high-risk place to more likely become an SSP in different waves of COVID-19 by using regression models. The results indicate that some places had very high transmission risk and suffered from repeated COVID-19 outbreaks over the four waves, and some of these high-risk places were SSPs where most (about 80%) of the COVID-19 transmission occurred due to their intense spatial interactions with other places. Further, we find that high-risk places with dense urban renewal buildings and high median monthly household rent-to-income ratio have higher odds of being SSPs. The results also imply that the associations between built-environment and socio-demographic features with the high-risk places and SSPs are dynamic over time. The implications for better policymaking during the COVID-19 pandemic are discussed.

摘要

先前的研究表明,大多数 COVID-19 感染是由少数个人在少数高风险场所(例如酒吧或社交聚会场所)传播的。这些人通常被称为超级传播者,会将病毒传播给数量异常多的人。此外,少数发生这种情况的超级传播场所(SSP)导致了大量 COVID-19 的传播。在这项研究中,我们提出了一个空间网络框架,用于识别不成比例地传播 COVID-19 的 SSP。我们使用香港确诊病例的个人活动数据,首先使用时空核密度方法(STKDE)确定前四个 COVID-19 波的高风险场所。然后,我们通过构建整合确诊病例流动强度的空间网络来识别这些高风险场所中的 SSP。我们还通过回归模型研究了在不同的 COVID-19 波中,哪些建筑环境和社会人口特征会使高风险场所更有可能成为 SSP。结果表明,一些地方的传播风险非常高,在四个波次中都遭受了反复的 COVID-19 爆发,其中一些高风险场所是 SSP,在这些地方,由于与其他地方的强烈空间相互作用,发生了大部分(约 80%)的 COVID-19 传播。此外,我们发现密集的城市更新建筑和高中位数月租金收入比的高风险场所成为 SSP 的几率更高。研究结果还表明,建筑环境和社会人口特征与高风险场所和 SSP 之间的关联是随时间动态变化的。讨论了这些结果对 COVID-19 大流行期间更好的决策制定的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcfb/8501223/e6a50084dadb/gr1_lrg.jpg

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