Analytical Sciences Division, CSIR-Indian Institute of Petroleum, Haridwar Road, Dehradun 248005, Uttarakhand, India; Material Resource Efficiency Division, CSIR-Indian Institute of Petroleum, Haridwar Road, Dehradun 248005, Uttarakhand, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Campus, Ghaziabad 201002, India.
Material Resource Efficiency Division, CSIR-Indian Institute of Petroleum, Haridwar Road, Dehradun 248005, Uttarakhand, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-HRDC Campus, Ghaziabad 201002, India.
Bioresour Technol. 2022 Jan;343:126121. doi: 10.1016/j.biortech.2021.126121. Epub 2021 Oct 12.
Polycyclic aromatic hydrocarbons (PAHs) are hazardous environmental pollutants with widespread and well-recognized health concerns. Amidst more than a hundred known PAHs, 16 are categorized as priority pollutants. Use of widely diverse biological machinery comprising bacteria, fungi, and algae harnessed from contaminated sites has emerged as an ecologically safe and sustainable approach for PAH degradation. The potential of these biological systems has been thoroughly examined to maximize the degradation of specific PAHs by understanding their detailed biochemical pathways, enzymatic system, and gene organization. Recent advancements in microbial genetic engineering and metabolomics using modern analytical tools have facilitated the bioremediation of such xenobiotics. This review explores the role of microbes, their biochemical pathways, genetic regulation of metabolic pathways, and the effect of biosurfactants against the backdrop of PAH substrate structures.
多环芳烃（PAHs）是具有广泛且公认的健康问题的危险环境污染物。在已知的一百多种 PAHs 中，有 16 种被归类为优先污染物。利用从污染地点采集的细菌、真菌和藻类等多种不同的生物机制，已经成为一种生态安全且可持续的 PAH 降解方法。这些生物系统的潜力已经得到了充分的研究，通过了解其详细的生化途径、酶系统和基因组织，以最大限度地降解特定的 PAHs。利用现代分析工具进行微生物遗传工程和代谢组学的最新进展，促进了此类外来化合物的生物修复。本文综述了微生物的作用、它们的生化途径、代谢途径的遗传调控以及生物表面活性剂对抗 PAH 基质结构的影响。
