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迈向生物医学和神经科学研究的反种族主义方法。

Toward an Anti-Racist Approach to Biomedical and Neuroscience Research.

机构信息

Department of Physiology, School of Medicine

Neuroscience Center of Excellence.

出版信息

J Neurosci. 2021 Oct 20;41(42):8669-8672. doi: 10.1523/JNEUROSCI.1319-21.2021.

DOI:10.1523/JNEUROSCI.1319-21.2021
PMID:34670866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8528500/
Abstract

Racism is a threat to public health. Race is a sociopolitical construct that has been used for generations to create disparities in educational access, housing conditions, exposure to environmental contaminants, and access to health care. Collectively, these disparities have a negative impact on the health of non-white Americans. The National Institutes of Health (NIH) funds biomedical research, including basic neuroscience research, aimed at understanding the mechanisms and consequences of health and disease in Americans. NIH has recently acknowledged its own structural racism, the disadvantage this perpetuates in the biomedical research enterprise, and has announced its commitment to eliminating these disparities. Here, we discuss different rates of disease in U.S. citizens from different racial backgrounds. We next describe ways in which the biomedical research enterprise (1) has contributed to health disparities and (2) can contribute to the solving this problem. Based on our own scientific expertise, we use neuroscience in general and mental health/addiction disorders more specifically as examples of a broader issue. The NIH, including its neuroscience-focused Institutes, and NIH-funded scientists, including neuroscientists, should prioritize research topics that reflect the health conditions that affect all Americans, not just white Americans.

摘要

种族主义是公共卫生的威胁。种族是一种社会政治结构,几代人以来一直被用来在教育机会、住房条件、接触环境污染物以及获得医疗保健方面造成差异。这些差异共同对非裔美国人的健康产生负面影响。美国国立卫生研究院 (NIH) 资助生物医学研究,包括基础神经科学研究,旨在了解美国人健康和疾病的机制和后果。NIH 最近承认了其自身的结构性种族主义,以及这种种族主义在生物医学研究企业中造成的不利影响,并宣布致力于消除这些差异。在这里,我们讨论了来自不同种族背景的美国公民的不同疾病发病率。接下来,我们描述了生物医学研究企业(1)如何导致健康差异,以及(2)如何有助于解决这个问题。基于我们自己的科学专业知识,我们以神经科学为例,更具体地说是以精神健康/成瘾障碍为例,来说明更广泛的问题。NIH,包括其专注于神经科学的研究所,以及 NIH 资助的科学家,包括神经科学家,应该优先考虑反映影响所有美国人的健康状况的研究课题,而不仅仅是白人美国人。

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本文引用的文献

1
Affirming NIH's commitment to addressing structural racism in the biomedical research enterprise.美国国立卫生研究院承诺致力于解决生物医学研究领域的结构性种族主义问题。
Cell. 2021 Jun 10;184(12):3075-3079. doi: 10.1016/j.cell.2021.05.014.
2
Associations of topic-specific peer review outcomes and institute and center award rates with funding disparities at the National Institutes of Health.特定主题同行评审结果、机构和中心奖励率与美国国立卫生研究院资金分配差距的关联。
Elife. 2021 Apr 13;10:e67173. doi: 10.7554/eLife.67173.
3
Fund Black scientists.资助黑人科学家。
Cell. 2021 Feb 4;184(3):561-565. doi: 10.1016/j.cell.2021.01.011. Epub 2021 Jan 26.
4
Racial inequity in grant funding from the US National Institutes of Health.美国国立卫生研究院拨款中的种族不平等现象。
Elife. 2021 Jan 18;10:e65697. doi: 10.7554/eLife.65697.
5
Variation in racial/ethnic disparities in COVID-19 mortality by age in the United States: A cross-sectional study.美国 COVID-19 死亡率的种族/民族差异随年龄变化的情况:一项横断面研究。
PLoS Med. 2020 Oct 20;17(10):e1003402. doi: 10.1371/journal.pmed.1003402. eCollection 2020 Oct.
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Neurobiological consequences of racial disparities and environmental risks: a critical gap in understanding psychiatric disorders.种族差异和环境风险的神经生物学后果:理解精神疾病方面的一个关键差距。
Neuropsychopharmacology. 2020 Jul;45(8):1247-1250. doi: 10.1038/s41386-020-0681-4. Epub 2020 Apr 24.
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Topic choice contributes to the lower rate of NIH awards to African-American/black scientists.课题选择导致美国国立卫生研究院(NIH)授予非裔美国/黑人科学家的奖项较少。
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