Department of Women's and Children's Health, Uppsala University, 75237 Uppsala, Sweden.
Faculty of Health, Social Care & Medicine, Edge Hill University, Ormskirk L39 4QP, UK.
Nutrients. 2021 Sep 25;13(10):3373. doi: 10.3390/nu13103373.
Anthropometric indicators of general and abdominal obesity can predict cardiovascular disease outcomes. Their performance in predicting hypertension (HTN) varies across populations. We aimed to analyze the relationship of body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR) and conicity index (CI) with HTN, to examine their predictive performance and to determine their optimal cut-offs in a nationally representative sample of Albanians aged 15-59 years ( = 20,635). Logistic regression models were fitted and sex-specific receiver-operating characteristic (ROC) curves were constructed. The indicators were positively associated with HTN. Sex modified the relationships, as associations appeared significantly stronger among females than males in the highest categories of the indicators. The area under ROC curves (AUCs) for BMI were 0.729 (95% confidence interval (CI): 0.720-0.738) among females and 0.648 (95% CI: 0.633-0.663) among males, and AUCs for WHtR were 0.725 (95% CI: 0.716-0.734) among females and 0.637 (95% CI: 0.622-0.652) among males. However, the AUCs for BMI and WHtR did not differ significantly among females ( = 0.279) and males ( = 0.227). BMI outperformed WC and CI in both sexes. The optimal BMI cut-offs were 27.0 kg/m among females and 25.6 kg/m among males, and that for WHtR were 0.53 among females and 0.54 among males. BMI and WHtR demonstrated similar discriminatory power, and the identified cut-offs may inform initiatives for structured HTN screening in Albania.
人体测量学指标(包括一般肥胖和腹型肥胖)可预测心血管疾病结局。其预测高血压(HTN)的性能在不同人群中有所差异。我们旨在分析体重指数(BMI)、腰围(WC)、腰高比(WHtR)和锥形指数(CI)与 HTN 的关系,检验其预测性能,并确定它们在一个具有全国代表性的 15-59 岁阿尔巴尼亚人群样本中的最佳截断值(n=20635)。我们拟合了逻辑回归模型,并构建了性别特异性的接收者操作特征(ROC)曲线。结果显示,这些指标与 HTN 呈正相关。性别对这些关系有影响,因为在指标的最高类别中,女性的关联明显强于男性。BMI 的 ROC 曲线下面积(AUC)在女性中为 0.729(95%置信区间(CI):0.720-0.738),在男性中为 0.648(95% CI:0.633-0.663),WHtR 的 AUC 在女性中为 0.725(95% CI:0.716-0.734),在男性中为 0.637(95% CI:0.622-0.652)。然而,BMI 和 WHtR 的 AUC 在女性(=0.279)和男性(=0.227)之间没有显著差异。在两性中,BMI 均优于 WC 和 CI。最佳 BMI 截断值在女性中为 27.0kg/m,在男性中为 25.6kg/m,WHtR 的最佳截断值在女性中为 0.53,在男性中为 0.54。BMI 和 WHtR 表现出相似的区分能力,所确定的截断值可能为阿尔巴尼亚开展结构化 HTN 筛查提供信息。