1st Department of Surgery, Nikaia General Hospital, Nikaia, Greece.
2 Department of Propaedeutic Surgery, National and Kapodistrian University of Athens, Athens, Greece.
In Vivo. 2021 Nov-Dec;35(6):3569-3574. doi: 10.21873/invivo.12660.
BACKGROUND/AIM: Surgical site infections (SSI) are associated with increased morbidity and mortality, and they occur more frequently during unplanned emergency surgical (ES) procedures rather than elective. Our aim was to determine the incidence of SSI within our ES cohort and to identify risk factors for SSI.
Data from consecutive patients undergoing ES in a single institution during a 5-year period were prospectively collected and analyzed.
A total of 838 consecutive patients were included. The median age was 52 (IQR=25-71) years and some 368 (44%) were female. 157 (18.7%) of those patients developed SSI. The most commonly isolated pathogen was E. Coli (55.4%) followed by Staphylococcus Aureus (40.1%). The 30-day mortality rate of patients who presented SSIs was 14.6% compared to 6.8% of patients without SSI (p=0.002). Multivariable analysis showed that the type of wound, American Society of Anesthesiology score, severity and duration of surgery >90 min were independent risk factors for the occurrence of SSI.
Identification of modifiable causative factors for SSI within an ES unit is paramount as they can critically impact postoperative outcomes.
背景/目的:手术部位感染(SSI)与发病率和死亡率增加有关,并且在计划外的紧急外科(ES)手术中比择期手术更常发生。我们的目的是确定我们的 ES 患者队列中 SSI 的发生率,并确定 SSI 的危险因素。
在一个 5 年期间,连续对在一个机构中接受 ES 的患者进行前瞻性数据收集和分析。
共纳入 838 例连续患者。中位年龄为 52 岁(IQR=25-71),其中 368 例(44%)为女性。157 例(18.7%)患者发生 SSI。最常分离的病原体是大肠杆菌(55.4%),其次是金黄色葡萄球菌(40.1%)。发生 SSI 的患者 30 天死亡率为 14.6%,而无 SSI 的患者为 6.8%(p=0.002)。多变量分析显示,伤口类型、美国麻醉医师协会评分、手术严重程度和持续时间>90 分钟是 SSI 发生的独立危险因素。
在 ES 病房中确定可改变的 SSI 致病因素至关重要,因为它们会严重影响术后结果。