Department of Epidemiology and Health Statistics, The School of Public Health, Qingdao University, No. 308 Ningxia Road, QingdaoShandong, 266021, China.
Qingdao Municipal Center for Disease Control and Prevention of Qingdao, Qingdao, Institute of Preventive Medicine, Qingdao, 266034, Shandong, China.
Sci Rep. 2021 Oct 25;11(1):21020. doi: 10.1038/s41598-021-00507-z.
Little attention has been paid to the relationship between air pollutants and varicella among adults. We used data collected in Qingdao, China from 2014 to 2019. A combination of quasi-Poisson generalized linear model (GLM) and distributed lag non-linear model (DLNM) was applied to evaluate the association between exposure to air pollutants and varicella. And the effects of exposure to extremely high concentration (at 97.5th percentile) and low concentration (at 2.5th percentile) of air pollutants on varicella were also calculated. The level II of GB3095-2012 was used as the reference. A 10 μg/m increase of PM was significantly associated with an increased risk of varicella (lag day: 4, 5 and 6). The negative associations were found for NO per 10 μg/m increase from lag 15 to 19 day. The high PM concentration (135 μg/m) was significantly associated with the increased risk of varicella (lag day: 6, 7). For NO, the negative association was found at high concentration (75 μg/m) on lag 15 to 20 day; and the positive relationship was shown at low concentration (10 μg/m) on lag 15 to 20 day. Exposure to PM and NO were significantly associated with the risk of varicella among adults.
人们对成年人中空气污染物与水痘之间的关系关注较少。我们使用了 2014 年至 2019 年在中国青岛收集的数据。采用拟泊松广义线性模型（GLM）和分布滞后非线性模型（DLNM）相结合的方法来评估暴露于空气污染物与水痘之间的关联。并计算了暴露于极高浓度（第 97.5 百分位数）和低浓度（第 2.5 百分位数）空气污染物对水痘的影响。采用 GB3095-2012 二级标准作为参考。PM 每增加 10μg/m，水痘的发病风险显著增加（滞后日：4、5 和 6）。从滞后 15 天到 19 天，NO 每增加 10μg/m，呈负相关。高 PM 浓度（135μg/m）与水痘发病风险增加显著相关（滞后日：6、7）。对于 NO，在高浓度（75μg/m）时，滞后 15 天到 20 天呈负相关；在低浓度（10μg/m）时，滞后 15 天到 20 天呈正相关。暴露于 PM 和 NO 与成年人水痘发病风险显著相关。
