Department of Epidemiology and Biostatistics, School of Population Health, University of Queensland, Brisbane, QLD 4006, Australia.
BMJ. 2013 Dec 9;347:f7139. doi: 10.1136/bmj.f7139.
To better understand the burden of air pollution on deaths, we examined the effects of air pollutants on years of life lost (YLL) in Beijing, China.
Retrospective regression analysis using daily time series.
8 urban districts in Beijing, China.
80 515 deaths (48 802 male, 31 713 female) recorded by the Beijing death classification system during 2004-08.
Associations between daily YLL and ambient air pollutants (particulate matter with aerodynamic diameter <2.5 µm (PM2.5), PM10, SO2, and NO2), after adjusting for long term trends, seasonality, day of the week, and weather conditions. We also examined mortality risk related to air pollutants.
Mean concentrations of daily PM2.5, PM10, SO2 and NO2 were 105.1 μg/m(3), 144.6 μg/m(3), 48.6 μg/m(3), and 64.2 μg/m(3), respectively. All air pollutants had significant effects on years of life lost when we used single pollutant models. An interquartile range (IQR) increase in PM2.5, PM10, SO2, and NO2 was related to YLL increases of 15.8, 15.8, 16.2, and 15.1 years, respectively. The effects of air pollutants on YLL appeared acutely and lasted for two days (lag 0-1); these effects associated with an IQR increase in PM2.5 were greater in women than men (11.1 (95% confidence interval 4.7 to 17.5) v 4.7 (-2.9 to 12.3) YLL) and in people aged up to 65 years than those older than 65 years (12.0 (2.9 to 21) v 3.8 (-0.9 to 8.6) YLL). The mortality risk associated with an IQR increase in PM2.5 was greater for people older than 65 years (2.5% (95% confidence interval 0.6% to 4.5%) increase of mortality) than those aged up to 65 years (0.7% (-0.8% to 2.2%)).
YLL provides a complementary measure for examining the effect of air pollutants on mortality. Increased YLL are associated with increased air pollution. This study highlights the need to reduce air pollution in Beijing, China, to protect the health of the population.
为了更好地了解空气污染对死亡人数的影响,我们研究了空气污染物对北京市寿命损失年(years of life lost,YLL)的影响。
采用每日时间序列的回顾性回归分析。
中国北京市 8 个城区。
2004-08 年期间,北京市死因分类系统记录的 80515 例死亡(48802 例男性,31713 例女性)。
调整长期趋势、季节性、星期几和天气条件后,每日 YLL 与环境空气污染物(空气动力学直径<2.5 µm 的颗粒物(PM2.5)、PM10、SO2 和 NO2)之间的关联。我们还检查了与空气污染物相关的死亡率风险。
每日 PM2.5、PM10、SO2 和 NO2 的平均浓度分别为 105.1μg/m3、144.6μg/m3、48.6μg/m3 和 64.2μg/m3。当我们使用单一污染物模型时,所有空气污染物对寿命损失年都有显著影响。PM2.5、PM10、SO2 和 NO2 的四分位距(interquartile range,IQR)增加分别与 YLL 增加 15.8、15.8、16.2 和 15.1 年相关。空气污染物对 YLL 的影响表现出急性,持续两天(lag 0-1);与 IQR 增加 PM2.5 相关的这些影响在女性中大于男性(11.1(95%置信区间 4.7 至 17.5)比 4.7(-2.9 至 12.3)YLL)和在 65 岁以下人群中大于 65 岁人群(12.0(2.9 至 21)比 3.8(-0.9 至 8.6)YLL)。与 PM2.5 的 IQR 增加相关的死亡率风险在 65 岁以上人群中大于 65 岁以下人群(2.5%(95%置信区间 0.6%至 4.5%)的死亡率增加)(0.7%(-0.8%至 2.2%)。
YLL 为评估空气污染物对死亡率的影响提供了一种补充措施。寿命损失年的增加与空气污染的增加有关。本研究强调了需要减少中国北京市的空气污染,以保护人群的健康。